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Research · head to head

OpenEye, Cadence Molecular Sciences vs SurveySparrow

OpenEye, Cadence Molecular Sciences logo

OpenEye, Cadence Molecular Sciences

Research

Computational chemistry toolkits and the Orion cloud platform, now inside Cadence

From
On request
Rated
-
Full reviewWebsite
SurveySparrow logo

SurveySparrow

Research

Survey and feedback platform for employee engagement

From
Free
Rated
-
Full reviewWebsite

The short version

  • Only SurveySparrow has a free tier, so it costs nothing to try first.
  • Each has a real cost: OpenEye, Cadence Molecular Sciences the free Public Domain Research Licence requires surrendering intellectual property rights and publishing results into the public domain, which rules it out for any academic group with a technology transfer office or patent ambitions.; SurveySparrow the free plan allows 75 responses per quarter, 3 active surveys and 10 questions per survey
  • They diverge on capability: OpenEye, Cadence Molecular Sciences covers OMEGA, SurveySparrow covers Survey creation.
  • Prices and features above were last checked on 31 August 2026.

Where they differ

Only the attributes on which OpenEye, Cadence Molecular Sciences and SurveySparrow actually diverge.

Attributes where OpenEye, Cadence Molecular Sciences and SurveySparrow differ
AttributeOpenEye, Cadence Molecular SciencesSurveySparrow
Starting priceOn requestFree
Pricing modelquoteusage-based
Free tierNoYes
PlatformsLinux, Windows, macOS, Web, APIWeb
FoundedUnknown2011

Identical on both: user rating (Not yet rated), category (Research).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in OpenEye, Cadence Molecular Sciences

  • OMEGA
  • ROCS
  • ROCS X
  • Orion platform
  • Programmatic toolkits
  • Academic routes
  • Structure preparation
  • Docking and scoring

Only in SurveySparrow

  • Survey creation
  • Engagement surveys
  • Pulse surveys
  • Analytics dashboard
  • Mobile app
  • Custom templates
  • Action planning
  • Reporting

What people use each for

The jobs each tool is most often brought in to do.

OpenEye, Cadence Molecular Sciences

  • A pharmaceutical discovery team screening a multi-billion compound library by three-dimensional shape rather than by two-dimensional similaritynot SurveySparrow
  • A computational chemist embedding conformer generation into an internal pipeline through the Python toolkitsnot SurveySparrow
  • A university group publishing openly that can accept the public domain licence terms in exchange for zero costnot SurveySparrow
  • A biotech scaling virtual screening on cloud compute without building its own clusternot SurveySparrow

SurveySparrow

  • Running conversational surveys and NPS programmesnot OpenEye, Cadence Molecular Sciences
  • Collecting employee and customer feedback on a schedulenot OpenEye, Cadence Molecular Sciences
  • Embedding surveys in websites, email and chat channelsnot OpenEye, Cadence Molecular Sciences

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

OpenEye, Cadence Molecular Sciences

  • The free Public Domain Research Licence requires surrendering intellectual property rights and publishing results into the public domain, which rules it out for any academic group with a technology transfer office or patent ambitions.
  • Free academic licences are renewable but re-evaluated annually with no guarantee of continuation, so a multi-year research programme has no assured software entitlement beyond the current year.
  • OpenEye now sits inside Cadence Design Systems, whose core business is chip design, so the roadmap and licensing culture are set by a company for which molecular sciences is one growth line among several.
  • Commercial pricing is entirely unpublished and structured as annual subscriptions with separate Orion compute, making total cost of a screening programme hard to forecast before contracting.
  • The toolkits assume real computational chemistry expertise; they are libraries and applications for specialists, not an interface a medicinal chemist can drive without training.

SurveySparrow

  • The free plan allows 75 responses per quarter, 3 active surveys and 10 questions per survey
  • The Basic and Starter plans include a single user; extra users cost $49 per user per month
  • Responses are metered per month and additional responses or API calls require a custom quote from sales
  • Custom branding requires the Business plan
  • CSS customisation, auto translation, Key Driver Analysis and HIPAA compliance are Enterprise only
  • The advertised savings of up to 40 percent require annual billing rather than quarterly

Pricing, plan by plan

OpenEye, Cadence Molecular Sciences

On request
  • Commercial licence$undefined/year
    • Annual subscription priced through Cadence sales
    • Toolkits and applications licensed separately from the Orion platform
    • Orion compute billed on top of software entitlements
  • Academic Package$undefined/year
    • Paid annual subscription for university groups under ten members
    • Includes support
    • Researchers retain intellectual property rights
  • Public Domain Research LicenceFree
    • No cost
    • No support of any kind
    • No intellectual property rights retained

SurveySparrow

Free
  • FreeFree
    • Basic surveys
    • Limited questions
    • Standard reports
  • Pro$undefined/month
    • Advanced surveys
    • Unlimited questions
    • Advanced analytics

Which should you pick?

Choose OpenEye, Cadence Molecular Sciences if

  • You need omega.
  • You work on Linux, Windows, macOS, Web, API.
  • You also want rocs.
OpenEye, Cadence Molecular Sciences review

Choose SurveySparrow if

  • You need survey creation.
  • You want to start without paying.
  • You also want engagement surveys.
SurveySparrow review

Questions people ask

Is OpenEye, Cadence Molecular Sciences or SurveySparrow better?
Neither clearly leads. OpenEye, Cadence Molecular Sciences starts at On request and SurveySparrow at Free, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, OpenEye, Cadence Molecular Sciences or SurveySparrow?
SurveySparrow has a free tier; the other does not. Paid plans start at On request for OpenEye, Cadence Molecular Sciences and Free for SurveySparrow.
Does OpenEye, Cadence Molecular Sciences or SurveySparrow run on more platforms?
OpenEye, Cadence Molecular Sciences runs on Linux, Windows, macOS, Web, API. SurveySparrow runs on Web.
Can I use SurveySparrow for free?
Yes. SurveySparrow has a free tier, so you can try it without paying. OpenEye, Cadence Molecular Sciences starts at On request.
What is OpenEye, Cadence Molecular Sciences best used for?
OpenEye, Cadence Molecular Sciences is most often used for a pharmaceutical discovery team screening a multi-billion compound library by three-dimensional shape rather than by two-dimensional similarity, a computational chemist embedding conformer generation into an internal pipeline through the python toolkits, a university group publishing openly that can accept the public domain licence terms in exchange for zero cost, a biotech scaling virtual screening on cloud compute without building its own cluster. Of those, a pharmaceutical discovery team screening a multi-billion compound library by three-dimensional shape rather than by two-dimensional similarity and a computational chemist embedding conformer generation into an internal pipeline through the python toolkits are not what SurveySparrow is typically brought in for.
What can OpenEye, Cadence Molecular Sciences do that SurveySparrow cannot?
OpenEye, Cadence Molecular Sciences covers OMEGA, ROCS, ROCS X, Orion platform. SurveySparrow covers Survey creation, Engagement surveys, Pulse surveys, Analytics dashboard.

Answered from the vendors’ own pages

OpenEye, Cadence Molecular Sciences: Is OpenEye still OpenEye?

It trades as OpenEye, Cadence Molecular Sciences, and is part of Cadence Design Systems following acquisition. The product names OMEGA, ROCS and Orion continue.

SurveySparrow: Does SurveySparrow offer a free plan?

Yes, SurveySparrow offers a forever free plan with 3 active surveys, 10 questions per survey, and 75 responses per quarter. No credit card is required to sign up.

Source
OpenEye, Cadence Molecular Sciences: Can academics use it for free?

Yes, through the Public Domain Research Licence or a Teaching Licence, but both come with no support and no intellectual property rights. Keeping IP rights and support requires the paid Academic Package.

SurveySparrow: How much do SurveySparrow's paid plans cost?

SurveySparrow does not publish specific pricing amounts on its website. Basic, Starter, and Business plans are available with varying response limits and user counts. Enterprise requires contacting the company for a custom quote.

Source
OpenEye, Cadence Molecular Sciences: What is ROCS X?

A machine learning enabled extension of ROCS shape search, built on the Orion platform, aimed at screening chemical spaces in the trillions of molecules.

SurveySparrow: Can I add more users to my SurveySparrow plan?

Yes, additional users can be added at $49 per month per user beyond what is included in each plan tier.

Source
OpenEye, Cadence Molecular Sciences: Is commercial pricing published?

No. Commercial licences are annual subscriptions quoted through Cadence sales, with Orion compute charged separately.

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