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Research · head to head

Attest vs OpenEye, Cadence Molecular Sciences

Attest logo

Attest

Research

Straightforward pricing for predictable research costs

From
On request
Rated
-
Full reviewWebsite
OpenEye, Cadence Molecular Sciences logo

OpenEye, Cadence Molecular Sciences

Research

Computational chemistry toolkits and the Orion cloud platform, now inside Cadence

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: Attest pricing is metered by credits, where one credit equals one survey question answered by one person, rather than a flat per seat rate; OpenEye, Cadence Molecular Sciences the free Public Domain Research Licence requires surrendering intellectual property rights and publishing results into the public domain, which rules it out for any academic group with a technology transfer office or patent ambitions.
  • Prices and features above were last checked on 31 August 2026.

Where they differ

Only the attributes on which Attest and OpenEye, Cadence Molecular Sciences actually diverge.

Attributes where Attest and OpenEye, Cadence Molecular Sciences differ
AttributeAttestOpenEye, Cadence Molecular Sciences
Pricing modelsubscriptionquote
PlatformsWebLinux, Windows, macOS, Web, API

Identical on both: starting price (On request), free tier (No), user rating (Not yet rated), category (Research).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Attest

Nothing recorded that OpenEye, Cadence Molecular Sciences does not also cover.

Only in OpenEye, Cadence Molecular Sciences

  • OMEGA
  • ROCS
  • ROCS X
  • Orion platform
  • Programmatic toolkits
  • Academic routes
  • Structure preparation
  • Docking and scoring

What people use each for

The jobs each tool is most often brought in to do.

Attest

  • Testing product concepts with global audiencesnot OpenEye, Cadence Molecular Sciences
  • Monitoring brand health across campaignsnot OpenEye, Cadence Molecular Sciences
  • Validating creative concepts before launchnot OpenEye, Cadence Molecular Sciences
  • Researching market trends in 70 languagesnot OpenEye, Cadence Molecular Sciences

OpenEye, Cadence Molecular Sciences

  • A pharmaceutical discovery team screening a multi-billion compound library by three-dimensional shape rather than by two-dimensional similaritynot Attest
  • A computational chemist embedding conformer generation into an internal pipeline through the Python toolkitsnot Attest
  • A university group publishing openly that can accept the public domain licence terms in exchange for zero costnot Attest
  • A biotech scaling virtual screening on cloud compute without building its own clusternot Attest

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Attest

  • Pricing is metered by credits, where one credit equals one survey question answered by one person, rather than a flat per seat rate
  • The Basic tier caps usage at 50,000 credits; going beyond it requires upgrading to Standard (100,000), Elite (200,000) or a custom plan above 400,000
  • Additional credits purchased mid year cost 10 percent more per credit than the plan rate

OpenEye, Cadence Molecular Sciences

  • The free Public Domain Research Licence requires surrendering intellectual property rights and publishing results into the public domain, which rules it out for any academic group with a technology transfer office or patent ambitions.
  • Free academic licences are renewable but re-evaluated annually with no guarantee of continuation, so a multi-year research programme has no assured software entitlement beyond the current year.
  • OpenEye now sits inside Cadence Design Systems, whose core business is chip design, so the roadmap and licensing culture are set by a company for which molecular sciences is one growth line among several.
  • Commercial pricing is entirely unpublished and structured as annual subscriptions with separate Orion compute, making total cost of a screening programme hard to forecast before contracting.
  • The toolkits assume real computational chemistry expertise; they are libraries and applications for specialists, not an interface a medicinal chemist can drive without training.

Pricing, plan by plan

Attest

On request
  • Basic$undefined/mo
    • Up to 50,000 credits
  • Standard$undefined/mo
    • Up to 100,000 credits
  • Elite$undefined/mo
    • Up to 200,000 credits
  • Custom$undefined/mo
    • Over 400,000+ credits

OpenEye, Cadence Molecular Sciences

On request
  • Commercial licence$undefined/year
    • Annual subscription priced through Cadence sales
    • Toolkits and applications licensed separately from the Orion platform
    • Orion compute billed on top of software entitlements
  • Academic Package$undefined/year
    • Paid annual subscription for university groups under ten members
    • Includes support
    • Researchers retain intellectual property rights
  • Public Domain Research LicenceFree
    • No cost
    • No support of any kind
    • No intellectual property rights retained

Which should you pick?

Choose Attest if

Nothing in the data separates Attest from OpenEye, Cadence Molecular Sciences on the points above - pick on price and on how each one feels to use.

Attest review

Choose OpenEye, Cadence Molecular Sciences if

  • You need omega.
  • You work on Linux, Windows, macOS, Web, API.
  • You also want rocs.
OpenEye, Cadence Molecular Sciences review

Questions people ask

Is Attest or OpenEye, Cadence Molecular Sciences better?
Neither clearly leads. Attest starts at On request and OpenEye, Cadence Molecular Sciences at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Attest or OpenEye, Cadence Molecular Sciences?
Attest starts at On request and OpenEye, Cadence Molecular Sciences at On request.
Does Attest or OpenEye, Cadence Molecular Sciences run on more platforms?
Attest runs on Web. OpenEye, Cadence Molecular Sciences runs on Linux, Windows, macOS, Web, API.
What is Attest best used for?
Attest is most often used for testing product concepts with global audiences, monitoring brand health across campaigns, validating creative concepts before launch, researching market trends in 70 languages. Of those, testing product concepts with global audiences and monitoring brand health across campaigns are not what OpenEye, Cadence Molecular Sciences is typically brought in for.
What can Attest do that OpenEye, Cadence Molecular Sciences cannot?
OpenEye, Cadence Molecular Sciences covers OMEGA, ROCS, ROCS X, Orion platform.

Answered from the vendors’ own pages

Attest: How does Attest's credit system work?

Attest uses a credit-based pricing system where one credit equals one survey answer from one respondent. For example, a 10-question survey completed by 500 people uses 5,000 credits. Only respondents who meet survey criteria consume credits from the qualifying question.

Source
OpenEye, Cadence Molecular Sciences: Is OpenEye still OpenEye?

It trades as OpenEye, Cadence Molecular Sciences, and is part of Cadence Design Systems following acquisition. The product names OMEGA, ROCS and Orion continue.

Attest: What plans does Attest offer?

Attest offers four subscription plans: Basic (up to 50,000 credits), Standard (up to 100,000 credits), Elite (up to 200,000 credits), and Custom (over 400,000+ credits). All plans include unlimited user seats, designated research expert, customer success team support, and access to 150+ million consumers across 59 countries in 70+ languages.

Source
OpenEye, Cadence Molecular Sciences: Can academics use it for free?

Yes, through the Public Domain Research Licence or a Teaching Licence, but both come with no support and no intellectual property rights. Keeping IP rights and support requires the paid Academic Package.

Attest: Can I purchase additional credits on Attest?

Yes. Additional credits are available as add-ons throughout the year. Add-on credits cost 10% more than the per-credit rate in annual plans.

Source
OpenEye, Cadence Molecular Sciences: What is ROCS X?

A machine learning enabled extension of ROCS shape search, built on the Orion platform, aimed at screening chemical spaces in the trillions of molecules.

OpenEye, Cadence Molecular Sciences: Is commercial pricing published?

No. Commercial licences are annual subscriptions quoted through Cadence sales, with Orion compute charged separately.

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