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Research · head to head

Marvin vs OpenEye, Cadence Molecular Sciences

Marvin logo

Marvin

Research

Qualitative research repository with AI notetaking, and an MCP server you can query from Claude

From
Free
Rated
-
Full reviewWebsite
OpenEye, Cadence Molecular Sciences logo

OpenEye, Cadence Molecular Sciences

Research

Computational chemistry toolkits and the Orion cloud platform, now inside Cadence

From
On request
Rated
-
Full reviewWebsite

The short version

  • Only Marvin has a free tier, so it costs nothing to try first.
  • Each has a real cost: Marvin transcription is inconsistent, with missing punctuation and specifically poor Portuguese accuracy reported, so non-English research teams spend the time cleaning up that the licence was meant to save.; OpenEye, Cadence Molecular Sciences the free Public Domain Research Licence requires surrendering intellectual property rights and publishing results into the public domain, which rules it out for any academic group with a technology transfer office or patent ambitions.
  • They diverge on capability: Marvin covers AI Notetaker, OpenEye, Cadence Molecular Sciences covers OMEGA.
  • Prices and features above were last checked on 31 August 2026.

Where they differ

Only the attributes on which Marvin and OpenEye, Cadence Molecular Sciences actually diverge.

Attributes where Marvin and OpenEye, Cadence Molecular Sciences differ
AttributeMarvinOpenEye, Cadence Molecular Sciences
Starting priceFreeOn request
Free tierYesNo
PlatformsWebLinux, Windows, macOS, Web, API

Identical on both: pricing model (quote), user rating (Not yet rated), category (Research).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Marvin

  • AI Notetaker
  • AI Moderated Interviewer
  • Ask AI
  • Deep Research
  • Thematic and emotion analysis
  • Clips and highlight reels
  • Virtual observation room
  • MCP server and API

Only in OpenEye, Cadence Molecular Sciences

  • OMEGA
  • ROCS
  • ROCS X
  • Orion platform
  • Programmatic toolkits
  • Academic routes
  • Structure preparation
  • Docking and scoring

What people use each for

The jobs each tool is most often brought in to do.

Marvin

  • A two-person research team that needs interviews transcribed, tagged and searchable without hiring an analyst or buying an enterprise repository.not OpenEye, Cadence Molecular Sciences
  • A product organisation where findings are never read, wanting product managers to query past research from Claude or ChatGPT instead of logging into a research tool.not OpenEye, Cadence Molecular Sciences
  • A team running discovery at volume that wants an AI moderator to conduct unmoderated interviews overnight and have them analysed by morning.not OpenEye, Cadence Molecular Sciences
  • A researcher who needs to send stakeholders a highlight reel of customer quotes rather than a slide deck summarising them.not OpenEye, Cadence Molecular Sciences

OpenEye, Cadence Molecular Sciences

  • A pharmaceutical discovery team screening a multi-billion compound library by three-dimensional shape rather than by two-dimensional similaritynot Marvin
  • A computational chemist embedding conformer generation into an internal pipeline through the Python toolkitsnot Marvin
  • A university group publishing openly that can accept the public domain licence terms in exchange for zero costnot Marvin
  • A biotech scaling virtual screening on cloud compute without building its own clusternot Marvin

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Marvin

  • Transcription is inconsistent, with missing punctuation and specifically poor Portuguese accuracy reported, so non-English research teams spend the time cleaning up that the licence was meant to save.
  • Speaker diarisation errors attribute moderator speech to the participant, and a misattributed quote propagates into themes and into the insight report you show stakeholders, which is a research credibility risk rather than a cosmetic bug.
  • SSO, EU or US data residency, PII redaction and a HIPAA BAA are bundled into a paid Compliance add-on available only from Pro upwards, so the headline Pro quote is never the real price for a regulated or European buyer.
  • Starter includes only two full seats, so a four-researcher team is forced to Pro on seat count alone, and the three-way split between full, collaborator and viewer seats makes cost modelling awkward when no paid tier is priced publicly.
  • Every paid tier is sales-gated with annual commitment typically required, so there is no monthly paid trial and no published seat cost to budget against before entering a sales cycle.
  • Integration coverage has gaps, with no Intercom connector despite repeated requests from teams wanting support conversations in the same repository, and reviewers describe the tags versus labels distinction in the interface as confusing.

OpenEye, Cadence Molecular Sciences

  • The free Public Domain Research Licence requires surrendering intellectual property rights and publishing results into the public domain, which rules it out for any academic group with a technology transfer office or patent ambitions.
  • Free academic licences are renewable but re-evaluated annually with no guarantee of continuation, so a multi-year research programme has no assured software entitlement beyond the current year.
  • OpenEye now sits inside Cadence Design Systems, whose core business is chip design, so the roadmap and licensing culture are set by a company for which molecular sciences is one growth line among several.
  • Commercial pricing is entirely unpublished and structured as annual subscriptions with separate Orion compute, making total cost of a screening programme hard to forecast before contracting.
  • The toolkits assume real computational chemistry expertise; they are libraries and applications for specialists, not an interface a medicinal chemist can drive without training.

Pricing, plan by plan

Marvin

Free
  • FreeFree
    • 2 full seats and 3 collaborator seats
    • 5 file uploads per month
    • AI notetaking and transcription
  • Starter$undefined/year
    • 2 full seats, 10 collaborator seats, 50 viewer seats
    • Unlimited uploads
    • Thematic analysis
  • Pro$undefined/year
    • 5 full seats, 15 collaborator seats, 100 viewer seats
    • Agentic Ask AI and Deep Research
    • Marvin MCP server and API
  • Enterprise$undefined/year
    • 5 full seats, 15 collaborator seats, unlimited viewer seats
    • Salesforce integration included
    • Dedicated support

OpenEye, Cadence Molecular Sciences

On request
  • Commercial licence$undefined/year
    • Annual subscription priced through Cadence sales
    • Toolkits and applications licensed separately from the Orion platform
    • Orion compute billed on top of software entitlements
  • Academic Package$undefined/year
    • Paid annual subscription for university groups under ten members
    • Includes support
    • Researchers retain intellectual property rights
  • Public Domain Research LicenceFree
    • No cost
    • No support of any kind
    • No intellectual property rights retained

Which should you pick?

Choose Marvin if

  • You need ai notetaker.
  • You want to start without paying.
  • You also want ai moderated interviewer.
Marvin review

Choose OpenEye, Cadence Molecular Sciences if

  • You need omega.
  • You work on Linux, Windows, macOS, Web, API.
  • You also want rocs.
OpenEye, Cadence Molecular Sciences review

Questions people ask

Is Marvin or OpenEye, Cadence Molecular Sciences better?
Neither clearly leads. Marvin starts at Free and OpenEye, Cadence Molecular Sciences at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Marvin or OpenEye, Cadence Molecular Sciences?
Marvin has a free tier; the other does not. Paid plans start at Free for Marvin and On request for OpenEye, Cadence Molecular Sciences.
Does Marvin or OpenEye, Cadence Molecular Sciences run on more platforms?
Marvin runs on Web. OpenEye, Cadence Molecular Sciences runs on Linux, Windows, macOS, Web, API.
Can I use Marvin for free?
Yes. Marvin has a free tier, so you can try it without paying. OpenEye, Cadence Molecular Sciences starts at On request.
What is Marvin best used for?
Marvin is most often used for a two-person research team that needs interviews transcribed, tagged and searchable without hiring an analyst or buying an enterprise repository., a product organisation where findings are never read, wanting product managers to query past research from claude or chatgpt instead of logging into a research tool., a team running discovery at volume that wants an ai moderator to conduct unmoderated interviews overnight and have them analysed by morning., a researcher who needs to send stakeholders a highlight reel of customer quotes rather than a slide deck summarising them.. Of those, a two-person research team that needs interviews transcribed, tagged and searchable without hiring an analyst or buying an enterprise repository. and a product organisation where findings are never read, wanting product managers to query past research from claude or chatgpt instead of logging into a research tool. are not what OpenEye, Cadence Molecular Sciences is typically brought in for.
What can Marvin do that OpenEye, Cadence Molecular Sciences cannot?
Marvin covers AI Notetaker, AI Moderated Interviewer, Ask AI, Deep Research. OpenEye, Cadence Molecular Sciences covers OMEGA, ROCS, ROCS X, Orion platform.

Answered from the vendors’ own pages

Marvin: Is there a genuinely free plan?

Yes. Two full seats, three collaborator seats and five file uploads a month at no cost. It is enough to evaluate the analysis quality on real interviews.

OpenEye, Cadence Molecular Sciences: Is OpenEye still OpenEye?

It trades as OpenEye, Cadence Molecular Sciences, and is part of Cadence Design Systems following acquisition. The product names OMEGA, ROCS and Orion continue.

Marvin: What does Pro cost?

Not published. Only the Free tier carries a price. Starter, Pro and Enterprise are all quoted.

OpenEye, Cadence Molecular Sciences: Can academics use it for free?

Yes, through the Public Domain Research Licence or a Teaching Licence, but both come with no support and no intellectual property rights. Keeping IP rights and support requires the paid Academic Package.

Marvin: Can I get SSO and EU data residency?

Yes, but as a separately priced Compliance add-on from Pro upwards, not included in any base tier. Price it into the quote from the start.

OpenEye, Cadence Molecular Sciences: What is ROCS X?

A machine learning enabled extension of ROCS shape search, built on the Orion platform, aimed at screening chemical spaces in the trillions of molecules.

Marvin: What is the MCP server for?

It lets Claude, ChatGPT or Copilot query your research repository directly with cited answers, so stakeholders get findings without opening Marvin.

OpenEye, Cadence Molecular Sciences: Is commercial pricing published?

No. Commercial licences are annual subscriptions quoted through Cadence sales, with Orion compute charged separately.

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