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Research · head to head

NVivo vs OpenEye, Cadence Molecular Sciences

NVivo logo

NVivo

Research

Easy-to-use, collaborative qualitative analysis software

From
On request
Rated
-
Full reviewWebsite
OpenEye, Cadence Molecular Sciences logo

OpenEye, Cadence Molecular Sciences

Research

Computational chemistry toolkits and the Orion cloud platform, now inside Cadence

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: NVivo base plan pricing not displayed on shop page; requires adding to cart or contacting sales; OpenEye, Cadence Molecular Sciences the free Public Domain Research Licence requires surrendering intellectual property rights and publishing results into the public domain, which rules it out for any academic group with a technology transfer office or patent ambitions.
  • Prices and features above were last checked on 31 August 2026.

Where they differ

Only the attributes on which NVivo and OpenEye, Cadence Molecular Sciences actually diverge.

Attributes where NVivo and OpenEye, Cadence Molecular Sciences differ
AttributeNVivoOpenEye, Cadence Molecular Sciences
PlatformsWebLinux, Windows, macOS, Web, API

Identical on both: starting price (On request), pricing model (quote), free tier (No), user rating (Not yet rated), category (Research).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in NVivo

Nothing recorded that OpenEye, Cadence Molecular Sciences does not also cover.

Only in OpenEye, Cadence Molecular Sciences

  • OMEGA
  • ROCS
  • ROCS X
  • Orion platform
  • Programmatic toolkits
  • Academic routes
  • Structure preparation
  • Docking and scoring

What people use each for

The jobs each tool is most often brought in to do.

NVivo

  • Qualitative data analysis for researchnot OpenEye, Cadence Molecular Sciences
  • Document and interview coding and analysisnot OpenEye, Cadence Molecular Sciences
  • Transcription and collaborative research projectsnot OpenEye, Cadence Molecular Sciences

OpenEye, Cadence Molecular Sciences

  • A pharmaceutical discovery team screening a multi-billion compound library by three-dimensional shape rather than by two-dimensional similaritynot NVivo
  • A computational chemist embedding conformer generation into an internal pipeline through the Python toolkitsnot NVivo
  • A university group publishing openly that can accept the public domain licence terms in exchange for zero costnot NVivo
  • A biotech scaling virtual screening on cloud compute without building its own clusternot NVivo

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

NVivo

  • Base plan pricing not displayed on shop page; requires adding to cart or contacting sales
  • Volume licensing (10+ seats) requires sales contact only
  • No free version available, only trials without specified duration

OpenEye, Cadence Molecular Sciences

  • The free Public Domain Research Licence requires surrendering intellectual property rights and publishing results into the public domain, which rules it out for any academic group with a technology transfer office or patent ambitions.
  • Free academic licences are renewable but re-evaluated annually with no guarantee of continuation, so a multi-year research programme has no assured software entitlement beyond the current year.
  • OpenEye now sits inside Cadence Design Systems, whose core business is chip design, so the roadmap and licensing culture are set by a company for which molecular sciences is one growth line among several.
  • Commercial pricing is entirely unpublished and structured as annual subscriptions with separate Orion compute, making total cost of a screening programme hard to forecast before contracting.
  • The toolkits assume real computational chemistry expertise; they are libraries and applications for specialists, not an interface a medicinal chemist can drive without training.

Pricing, plan by plan

NVivo

On request

No published plan breakdown. See the NVivo review.

OpenEye, Cadence Molecular Sciences

On request
  • Commercial licence$undefined/year
    • Annual subscription priced through Cadence sales
    • Toolkits and applications licensed separately from the Orion platform
    • Orion compute billed on top of software entitlements
  • Academic Package$undefined/year
    • Paid annual subscription for university groups under ten members
    • Includes support
    • Researchers retain intellectual property rights
  • Public Domain Research LicenceFree
    • No cost
    • No support of any kind
    • No intellectual property rights retained

Which should you pick?

Choose NVivo if

Nothing in the data separates NVivo from OpenEye, Cadence Molecular Sciences on the points above - pick on price and on how each one feels to use.

NVivo review

Choose OpenEye, Cadence Molecular Sciences if

  • You need omega.
  • You work on Linux, Windows, macOS, Web, API.
  • You also want rocs.
OpenEye, Cadence Molecular Sciences review

Questions people ask

Is NVivo or OpenEye, Cadence Molecular Sciences better?
Neither clearly leads. NVivo starts at On request and OpenEye, Cadence Molecular Sciences at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, NVivo or OpenEye, Cadence Molecular Sciences?
NVivo starts at On request and OpenEye, Cadence Molecular Sciences at On request.
Does NVivo or OpenEye, Cadence Molecular Sciences run on more platforms?
NVivo runs on Web. OpenEye, Cadence Molecular Sciences runs on Linux, Windows, macOS, Web, API.
What is NVivo best used for?
NVivo is most often used for qualitative data analysis for research, document and interview coding and analysis, transcription and collaborative research projects. Of those, qualitative data analysis for research and document and interview coding and analysis are not what OpenEye, Cadence Molecular Sciences is typically brought in for.
What can NVivo do that OpenEye, Cadence Molecular Sciences cannot?
OpenEye, Cadence Molecular Sciences covers OMEGA, ROCS, ROCS X, Orion platform.

Answered from the vendors’ own pages

NVivo: How much does NVivo cost?

NVivo pricing is not displayed on the public website. Base plan pricing varies by subscription type and region. Individual/small teams can purchase directly through shop.lumivero.com, while organizations with 10+ licenses must contact sales for quotes.

Source
OpenEye, Cadence Molecular Sciences: Is OpenEye still OpenEye?

It trades as OpenEye, Cadence Molecular Sciences, and is part of Cadence Design Systems following acquisition. The product names OMEGA, ROCS and Orion continue.

NVivo: What are NVivo add-on costs?

NVivo AI Assistant costs $250 per year. Transcription costs $499 per year (50 hours annually) or $30 one-time (60 minutes). Collaboration Cloud for team sharing costs $99 per year.

Source
OpenEye, Cadence Molecular Sciences: Can academics use it for free?

Yes, through the Public Domain Research Licence or a Teaching Licence, but both come with no support and no intellectual property rights. Keeping IP rights and support requires the paid Academic Package.

NVivo: Does NVivo offer a free version?

No free version of NVivo is available. Free trials are available at the product website, though trial duration is not specified. Individual users can purchase licenses directly through lumivero.com.

Source
OpenEye, Cadence Molecular Sciences: What is ROCS X?

A machine learning enabled extension of ROCS shape search, built on the Orion platform, aimed at screening chemical spaces in the trillions of molecules.

NVivo: Is NVivo AI Assistant included in subscription?

No, NVivo AI Assistant is a paid add-on costing $250 per year. However, through August 18-September 15, 2026, AI Assistant is free with annual NVivo + AI subscriptions using code BTSAI100.

Source
OpenEye, Cadence Molecular Sciences: Is commercial pricing published?

No. Commercial licences are annual subscriptions quoted through Cadence sales, with Orion compute charged separately.

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