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Healthcare · head to head

OpenClinica vs WebPT

OpenClinica logo

OpenClinica

Healthcare

Clinical trial EDC with a genuinely open source community edition alongside a quoted commercial platform

From
On request
Rated
-
Full reviewWebsite
WebPT logo

WebPT

Healthcare

EHR and practice management for physical therapy

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: OpenClinica the free community edition is a different and older product line from the commercial platform, so evaluating the open source build tells you little about what the paid product actually does.; WebPT no rate published on pricing page; vendor requires demo booking or sales contact for quotes
  • They diverge on capability: OpenClinica covers Open source community edition, WebPT covers Electronic Health Records.
  • Prices and features above were last checked on 31 August 2026.

Where they differ

Only the attributes on which OpenClinica and WebPT actually diverge.

Attributes where OpenClinica and WebPT differ
AttributeOpenClinicaWebPT
Pricing modelquotesubscription
PlatformsWeb, Self-hosted, iOS, AndroidCloud-based SaaS
FoundedUnknown2005

Identical on both: starting price (On request), free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in OpenClinica

  • Open source community edition
  • Electronic data capture
  • eConsent
  • eCOA and ePRO
  • Randomisation
  • EHR-to-EDC
  • Audit trail
  • Reporting and analytics

Only in WebPT

  • Electronic Health Records
  • Scheduling
  • Documentation
  • Patient Portal
  • Analytics
  • Billing
  • Insurance
  • PECOS

What people use each for

The jobs each tool is most often brought in to do.

OpenClinica

  • An academic coordinating centre running investigator-initiated trials that needs Part 11 compliant capture without an enterprise eClinical budgetnot WebPT
  • A registry or observational cohort study collecting structured data across many sites over yearsnot WebPT
  • A small device sponsor that needs eConsent and ePRO in the same system as its case report formsnot WebPT
  • An informatics group that wants to self-host the open source edition for a non-regulated internal studynot WebPT

WebPT

  • Multi-location physical therapy practices needing comprehensive billing automation and insurance processingnot OpenClinica
  • Rehabilitation therapy clinics requiring integrated AI-powered clinical documentationnot OpenClinica

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

OpenClinica

  • The free community edition is a different and older product line from the commercial platform, so evaluating the open source build tells you little about what the paid product actually does.
  • The vendor provides no support or services at all for the community edition, which means outages, patching, database upgrades and validation documentation are entirely your problem.
  • Commercial pricing is not published, so you cannot benchmark it against alternatives without entering a sales process, and third-party figures around USD 1,000 a month are indicative rather than contractual.
  • Study build is skilled work: complex edit checks, randomisation schemes and integrations usually mean paying for vendor or consultant configuration services on top of the licence, which is a frequently underestimated line in the budget.
  • As a smaller vendor than the large eClinical suites it has a thinner partner and consultant ecosystem, so finding experienced build staff or a CRO already fluent in the platform is harder than with the market incumbents.

WebPT

  • No rate published on pricing page; vendor requires demo booking or sales contact for quotes
  • Specific pricing amounts not disclosed despite three pricing tiers being described

Pricing, plan by plan

OpenClinica

On request
  • Community Edition$undefined/year
    • Free and open source under the LGPL
    • Self-hosted, on the older 3.x line
    • No vendor support or services of any kind
  • OpenClinica Enterprise$undefined/year
    • Pricing only through a sales process
    • Hosted and validated instance
    • EDC, eConsent, eCOA, randomisation and analytics modules

WebPT

On request

No published plan breakdown. See the WebPT review.

Which should you pick?

Choose OpenClinica if

  • You need open source community edition.
  • You work on Web, Self-hosted, iOS, Android.
  • You also want electronic data capture.
OpenClinica review

Choose WebPT if

  • You need electronic health records.
  • You work on Cloud-based SaaS.
  • You also want scheduling.
WebPT review

Questions people ask

Is OpenClinica or WebPT better?
Neither clearly leads. OpenClinica starts at On request and WebPT at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, OpenClinica or WebPT?
OpenClinica starts at On request and WebPT at On request.
Does OpenClinica or WebPT run on more platforms?
OpenClinica runs on Web, Self-hosted, iOS, Android. WebPT runs on Cloud-based SaaS.
What is OpenClinica best used for?
OpenClinica is most often used for an academic coordinating centre running investigator-initiated trials that needs part 11 compliant capture without an enterprise eclinical budget, a registry or observational cohort study collecting structured data across many sites over years, a small device sponsor that needs econsent and epro in the same system as its case report forms, an informatics group that wants to self-host the open source edition for a non-regulated internal study. Of those, an academic coordinating centre running investigator-initiated trials that needs part 11 compliant capture without an enterprise eclinical budget and a registry or observational cohort study collecting structured data across many sites over years are not what WebPT is typically brought in for.
What can OpenClinica do that WebPT cannot?
OpenClinica covers Open source community edition, Electronic data capture, eConsent, eCOA and ePRO. WebPT covers Electronic Health Records, Scheduling, Documentation, Patient Portal.

Answered from the vendors’ own pages

OpenClinica: Is OpenClinica free?

There is a genuinely free, LGPL licensed community edition you host yourself with no vendor support. The commercial platform with eConsent, eCOA and a validated hosted instance is quoted and paid.

WebPT: How much does WebPT cost?

WebPT pricing is customized based on your selected plan (Starter, Enhanced, or Ultimate) and any customizations your practice needs. Organizations must book a demo or contact sales to receive personalized pricing.

Source
OpenClinica: Is the open source version still maintained?

Yes, releases on the 3.x line continued through 2025, but it is a separate and older architecture from the commercial product.

WebPT: What are the three WebPT pricing tiers?

WebPT offers Starter for small cash-pay practices, Enhanced for growing practices that accept insurance and need billing, and Ultimate for larger practices requiring customization and advanced reporting.

Source
OpenClinica: Does it meet 21 CFR Part 11?

The commercial hosted platform is built for Part 11 and GCP compliance. If you self-host the community edition, compliance and validation are entirely your responsibility.

OpenClinica: What does the commercial version cost?

Not published. Third-party listings suggest enterprise arrangements from around USD 1,000 per month, but real cost depends on study count, subjects, modules and build services.

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