Softwr

Healthcare · head to head

Aidoc vs OpenClinica

Aidoc logo

Aidoc

Healthcare

FDA cleared radiology AI for triage and notification of time critical findings

From
On request
Rated
-
Full reviewWebsite
OpenClinica logo

OpenClinica

Healthcare

Clinical trial EDC with a genuinely open source community edition alongside a quoted commercial platform

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: Aidoc the clearances are for triage and notification in the CADt category, so the software may reorder a worklist but may not deliver a diagnosis or replace a read, and business cases built on reduced radiologist workload do not survive contact with the regulatory wording.; OpenClinica the free community edition is a different and older product line from the commercial platform, so evaluating the open source build tells you little about what the paid product actually does.
  • They diverge on capability: Aidoc covers Triage and notification, OpenClinica covers Open source community edition.
  • Prices and features above were last checked on 1 September 2026.

Where they differ

Only the attributes on which Aidoc and OpenClinica actually diverge.

Attributes where Aidoc and OpenClinica differ
AttributeAidocOpenClinica
PlatformsWeb, iOS, AndroidWeb, Self-hosted, iOS, Android

Identical on both: starting price (On request), pricing model (quote), free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Aidoc

  • Triage and notification
  • Intracranial haemorrhage
  • Pulmonary embolism
  • Large vessel occlusion
  • Pneumothorax on X-ray
  • aiOS platform
  • Clinical workflow notifications

Only in OpenClinica

  • Open source community edition
  • Electronic data capture
  • eConsent
  • eCOA and ePRO
  • Randomisation
  • EHR-to-EDC
  • Audit trail
  • Reporting and analytics

What people use each for

The jobs each tool is most often brought in to do.

Aidoc

  • A regional stroke centre that wants large vessel occlusion flagged and the neurointervention team notified before the radiologist dictatesnot OpenClinica
  • A trauma centre wanting cervical spine fracture and intra abdominal free gas prioritised in an overnight queue read by one on call radiologistnot OpenClinica
  • An oncology imaging programme that wants incidental pulmonary embolism caught on staging CTs ordered for a different questionnot OpenClinica
  • A health system that has bought AI from several vendors and wants one PACS integration through aiOS rather than one integration per algorithmnot OpenClinica

OpenClinica

  • An academic coordinating centre running investigator-initiated trials that needs Part 11 compliant capture without an enterprise eClinical budgetnot Aidoc
  • A registry or observational cohort study collecting structured data across many sites over yearsnot Aidoc
  • A small device sponsor that needs eConsent and ePRO in the same system as its case report formsnot Aidoc
  • An informatics group that wants to self-host the open source edition for a non-regulated internal studynot Aidoc

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Aidoc

  • The clearances are for triage and notification in the CADt category, so the software may reorder a worklist but may not deliver a diagnosis or replace a read, and business cases built on reduced radiologist workload do not survive contact with the regulatory wording.
  • Triage algorithms are tuned for sensitivity, so false positives are routine, and each one interrupts a radiologist. Sites that do not measure positive predictive value in their own case mix see clinician trust erode within months.
  • Pricing is per algorithm and per study volume with no published rate card, so the cost of a multi algorithm deployment escalates sharply and cannot be benchmarked before a sales conversation.
  • The clinical benefit accrues to stroke, trauma and cardiology service lines while the cost usually lands in the radiology or IT budget, which makes internal funding harder than the return on investment slides suggest.
  • Performance depends on scanner protocols and reconstruction settings, so results validated at one site do not transfer, and each deployment needs local validation work that is rarely budgeted for.

OpenClinica

  • The free community edition is a different and older product line from the commercial platform, so evaluating the open source build tells you little about what the paid product actually does.
  • The vendor provides no support or services at all for the community edition, which means outages, patching, database upgrades and validation documentation are entirely your problem.
  • Commercial pricing is not published, so you cannot benchmark it against alternatives without entering a sales process, and third-party figures around USD 1,000 a month are indicative rather than contractual.
  • Study build is skilled work: complex edit checks, randomisation schemes and integrations usually mean paying for vendor or consultant configuration services on top of the licence, which is a frequently underestimated line in the budget.
  • As a smaller vendor than the large eClinical suites it has a thinner partner and consultant ecosystem, so finding experienced build staff or a CRO already fluent in the platform is harder than with the market incumbents.

Pricing, plan by plan

Aidoc

On request
  • Aidoc$undefined/year
    • Annual subscription priced by algorithm and by study volume
    • aiOS platform integration licensed separately from individual algorithms
    • Multi algorithm bundles negotiated for enterprise deployments

OpenClinica

On request
  • Community Edition$undefined/year
    • Free and open source under the LGPL
    • Self-hosted, on the older 3.x line
    • No vendor support or services of any kind
  • OpenClinica Enterprise$undefined/year
    • Pricing only through a sales process
    • Hosted and validated instance
    • EDC, eConsent, eCOA, randomisation and analytics modules

Which should you pick?

Choose Aidoc if

  • You need triage and notification.
  • You work on Web, iOS, Android.
  • You also want intracranial haemorrhage.
Aidoc review

Choose OpenClinica if

  • You need open source community edition.
  • You work on Web, Self-hosted, iOS, Android.
  • You also want electronic data capture.
OpenClinica review

Questions people ask

Is Aidoc or OpenClinica better?
Neither clearly leads. Aidoc starts at On request and OpenClinica at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Aidoc or OpenClinica?
Aidoc starts at On request and OpenClinica at On request.
Does Aidoc or OpenClinica run on more platforms?
Aidoc runs on Web, iOS, Android. OpenClinica runs on Web, Self-hosted, iOS, Android.
What is Aidoc best used for?
Aidoc is most often used for a regional stroke centre that wants large vessel occlusion flagged and the neurointervention team notified before the radiologist dictates, a trauma centre wanting cervical spine fracture and intra abdominal free gas prioritised in an overnight queue read by one on call radiologist, an oncology imaging programme that wants incidental pulmonary embolism caught on staging cts ordered for a different question, a health system that has bought ai from several vendors and wants one pacs integration through aios rather than one integration per algorithm. Of those, a regional stroke centre that wants large vessel occlusion flagged and the neurointervention team notified before the radiologist dictates and a trauma centre wanting cervical spine fracture and intra abdominal free gas prioritised in an overnight queue read by one on call radiologist are not what OpenClinica is typically brought in for.
What can Aidoc do that OpenClinica cannot?
Aidoc covers Triage and notification, Intracranial haemorrhage, Pulmonary embolism, Large vessel occlusion. OpenClinica covers Open source community edition, Electronic data capture, eConsent, eCOA and ePRO.

Answered from the vendors’ own pages

Aidoc: Is Aidoc FDA cleared?

Yes, it holds multiple 510(k) clearances, but they are for computer aided triage and notification. It may prioritise a worklist and notify a team. It may not provide a diagnostic interpretation or replace a radiologist read.

OpenClinica: Is OpenClinica free?

There is a genuinely free, LGPL licensed community edition you host yourself with no vendor support. The commercial platform with eConsent, eCOA and a validated hosted instance is quoted and paid.

Aidoc: Does it reduce radiologist workload?

No. Every study still needs a full read. The benefit is in the order studies are read and how quickly a receiving specialty is activated, not in reading fewer studies.

OpenClinica: Is the open source version still maintained?

Yes, releases on the 3.x line continued through 2025, but it is a separate and older architecture from the commercial product.

Aidoc: Can I run other vendors AI through it?

Yes, that is what the aiOS platform layer is for, and for health systems with several AI vendors it is often the main reason to buy Aidoc at all.

OpenClinica: Does it meet 21 CFR Part 11?

The commercial hosted platform is built for Part 11 and GCP compliance. If you self-host the community edition, compliance and validation are entirely your responsibility.

Aidoc: Is pricing published?

No. It is quoted per algorithm and by annual study volume, and enterprise bundles are negotiated case by case.

OpenClinica: What does the commercial version cost?

Not published. Third-party listings suggest enterprise arrangements from around USD 1,000 per month, but real cost depends on study count, subjects, modules and build services.

Share

Related pages

More on Aidoc

More on OpenClinica

Keep looking

Other head to heads