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Healthcare · head to head

OpenClinica vs Visage Imaging

OpenClinica logo

OpenClinica

Healthcare

Clinical trial EDC with a genuinely open source community edition alongside a quoted commercial platform

From
On request
Rated
-
Full reviewWebsite
Visage Imaging logo

Visage Imaging

Healthcare

Server-side streaming PACS built for radiologists reading very large studies over thin connections

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: OpenClinica the free community edition is a different and older product line from the commercial platform, so evaluating the open source build tells you little about what the paid product actually does.; Visage Imaging pricing is per exam against a minimum annual volume, so an organisation whose imaging activity is flat pays a floor while a growing one sees the software line rise every year rather than amortise.
  • They diverge on capability: OpenClinica covers Open source community edition, Visage Imaging covers Server-side rendering.
  • Prices and features above were last checked on 1 September 2026.

Where they differ

Only the attributes on which OpenClinica and Visage Imaging actually diverge.

Attributes where OpenClinica and Visage Imaging differ
AttributeOpenClinicaVisage Imaging
PlatformsWeb, Self-hosted, iOS, AndroidWindows, macOS, Web, iOS, Cloud

Identical on both: starting price (On request), pricing model (quote), free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in OpenClinica

  • Open source community edition
  • Electronic data capture
  • eConsent
  • eCOA and ePRO
  • Randomisation
  • EHR-to-EDC
  • Audit trail
  • Reporting and analytics

Only in Visage Imaging

  • Server-side rendering
  • One Viewer
  • Native multi-dimensional tools
  • Digital breast tomosynthesis reading
  • Open archive
  • Cloud PACS operations
  • AI accelerator
  • On the fly patient jacket

What people use each for

The jobs each tool is most often brought in to do.

OpenClinica

  • An academic coordinating centre running investigator-initiated trials that needs Part 11 compliant capture without an enterprise eClinical budgetnot Visage Imaging
  • A registry or observational cohort study collecting structured data across many sites over yearsnot Visage Imaging
  • A small device sponsor that needs eConsent and ePRO in the same system as its case report formsnot Visage Imaging
  • An informatics group that wants to self-host the open source edition for a non-regulated internal studynot Visage Imaging

Visage Imaging

  • An academic health system whose radiologists read from home and cannot tolerate a thousand slice CT taking minutes to opennot OpenClinica
  • A breast imaging service moving to tomosynthesis where study sizes have made the existing PACS unusable at volumenot OpenClinica
  • A teleradiology group covering many client sites that needs one viewer rather than a client-specific workstation per contractnot OpenClinica
  • A health system mid migration that needs priors from three legacy archives assembled into one patient jacket before the data move finishesnot OpenClinica

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

OpenClinica

  • The free community edition is a different and older product line from the commercial platform, so evaluating the open source build tells you little about what the paid product actually does.
  • The vendor provides no support or services at all for the community edition, which means outages, patching, database upgrades and validation documentation are entirely your problem.
  • Commercial pricing is not published, so you cannot benchmark it against alternatives without entering a sales process, and third-party figures around USD 1,000 a month are indicative rather than contractual.
  • Study build is skilled work: complex edit checks, randomisation schemes and integrations usually mean paying for vendor or consultant configuration services on top of the licence, which is a frequently underestimated line in the budget.
  • As a smaller vendor than the large eClinical suites it has a thinner partner and consultant ecosystem, so finding experienced build staff or a CRO already fluent in the platform is harder than with the market incumbents.

Visage Imaging

  • Pricing is per exam against a minimum annual volume, so an organisation whose imaging activity is flat pays a floor while a growing one sees the software line rise every year rather than amortise.
  • Module breadth outside radiology is narrower than at Sectra or the large modality vendors, so a group planning to digitise pathology on the same platform will not find it here.
  • Server-side rendering shifts the cost to central infrastructure, so the saving on radiologist workstations is partly offset by what you spend on servers or cloud compute.
  • Pro Medicus concentrates on very large contracts, and smaller imaging groups report long sales cycles and little appetite from the vendor for deals below a certain volume.
  • Diagnostic AI is third party, surfaced through the accelerator framework rather than developed in house, so algorithm licensing, validation and monitoring remain the buyer problem.

Pricing, plan by plan

OpenClinica

On request
  • Community Edition$undefined/year
    • Free and open source under the LGPL
    • Self-hosted, on the older 3.x line
    • No vendor support or services of any kind
  • OpenClinica Enterprise$undefined/year
    • Pricing only through a sales process
    • Hosted and validated instance
    • EDC, eConsent, eCOA, randomisation and analytics modules

Visage Imaging

On request
  • Visage 7 enterprise contract$undefined/year
    • Transaction pricing per exam with a minimum annual volume commitment
    • Seven to ten year terms typical for health system contracts
    • Contract totals for major deals are disclosed by Pro Medicus to the ASX

Which should you pick?

Choose OpenClinica if

  • You need open source community edition.
  • You work on Web, Self-hosted, iOS, Android.
  • You also want electronic data capture.
OpenClinica review

Choose Visage Imaging if

  • You need server-side rendering.
  • You work on Windows, macOS, Web, iOS, Cloud.
  • You also want one viewer.
Visage Imaging review

Questions people ask

Is OpenClinica or Visage Imaging better?
Neither clearly leads. OpenClinica starts at On request and Visage Imaging at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, OpenClinica or Visage Imaging?
OpenClinica starts at On request and Visage Imaging at On request.
Does OpenClinica or Visage Imaging run on more platforms?
OpenClinica runs on Web, Self-hosted, iOS, Android. Visage Imaging runs on Windows, macOS, Web, iOS, Cloud.
What is OpenClinica best used for?
OpenClinica is most often used for an academic coordinating centre running investigator-initiated trials that needs part 11 compliant capture without an enterprise eclinical budget, a registry or observational cohort study collecting structured data across many sites over years, a small device sponsor that needs econsent and epro in the same system as its case report forms, an informatics group that wants to self-host the open source edition for a non-regulated internal study. Of those, an academic coordinating centre running investigator-initiated trials that needs part 11 compliant capture without an enterprise eclinical budget and a registry or observational cohort study collecting structured data across many sites over years are not what Visage Imaging is typically brought in for.
What can OpenClinica do that Visage Imaging cannot?
OpenClinica covers Open source community edition, Electronic data capture, eConsent, eCOA and ePRO. Visage Imaging covers Server-side rendering, One Viewer, Native multi-dimensional tools, Digital breast tomosynthesis reading.

Answered from the vendors’ own pages

OpenClinica: Is OpenClinica free?

There is a genuinely free, LGPL licensed community edition you host yourself with no vendor support. The commercial platform with eConsent, eCOA and a validated hosted instance is quoted and paid.

Visage Imaging: Who owns Visage Imaging?

Pro Medicus Limited, listed on the Australian Securities Exchange. That listing means major contract values and terms are publicly announced.

OpenClinica: Is the open source version still maintained?

Yes, releases on the 3.x line continued through 2025, but it is a separate and older architecture from the commercial product.

Visage Imaging: How is Visage priced?

Per exam, against a minimum annual volume, on multi-year terms. Because Pro Medicus discloses large contract totals and durations to the market, buyers can estimate a per exam rate before entering negotiation.

OpenClinica: Does it meet 21 CFR Part 11?

The commercial hosted platform is built for Part 11 and GCP compliance. If you self-host the community edition, compliance and validation are entirely your responsibility.

Visage Imaging: Is Visage 7 FDA cleared for diagnostic interpretation?

Yes, Visage 7 holds 510(k) clearance for diagnostic viewing including mammography and tomosynthesis on validated displays. Confirm the exact cleared modality list for your intended use.

OpenClinica: What does the commercial version cost?

Not published. Third-party listings suggest enterprise arrangements from around USD 1,000 per month, but real cost depends on study count, subjects, modules and build services.

Visage Imaging: Does it work as a full cloud PACS?

Yes, Visage 7 runs complete PACS operations in the cloud rather than cloud viewing over an on-premise archive.

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