Healthcare · head to head
Annalise.ai vs SilverCloud by Amwell

Annalise.ai
Healthcare
Multi-finding chest X-ray and head CT triage AI with FDA clearance on named findings, not on the whole model
- From
- On request
- Rated
- -

SilverCloud by Amwell
Healthcare
Guided digital cognitive behavioural therapy with a published randomised trial evidence base
- From
- On request
- Rated
- -
The short version
- Each has a real cost: Annalise.ai the United States cleared indication covers roughly ten findings for triage and notification, far fewer than the model reports, so a buyer who evaluates the full multi-finding output and then contracts in the United States gets a much narrower cleared use.; SilverCloud by Amwell the evidence base is for the guided model, and organisations that deploy SilverCloud as unstaffed self service get the completion rates of unguided self help, which is not what the trials measured.
- They diverge on capability: Annalise.ai covers Annalise Enterprise CXR, SilverCloud by Amwell covers Guided programmes.
- Prices and features above were last checked on 1 September 2026.
Where they differ
Only the attributes on which Annalise.ai and SilverCloud by Amwell actually diverge.
| Attribute | Annalise.ai | SilverCloud by Amwell |
|---|---|---|
| Platforms | Web, Cloud, On-premise | Web, iOS, Android |
Identical on both: starting price (On request), pricing model (quote), free tier (No), user rating (Not yet rated), category (Healthcare).
What each one covers
Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.
Only in Annalise.ai
- Annalise Enterprise CXR
- Annalise Enterprise CTB
- Triage and notification
- Worklist reprioritisation
- Localisation overlays
- Confidence output
- PACS-native deployment
- On-premise or cloud inference
Only in SilverCloud by Amwell
- Guided programmes
- Supporter review
- Symptom measurement
- Clinician dashboard
- Risk detection
- NHS talking therapies alignment
- Multiple deployment models
What people use each for
The jobs each tool is most often brought in to do.
Annalise.ai
- An emergency department wanting pneumothorax and intracranial haemorrhage pushed to the front of the reading queue overnight when cover is thinnestnot SilverCloud by Amwell
- A teleradiology provider covering many small hospitals that needs consistent triage before a human readsnot SilverCloud by Amwell
- A screening programme in Europe where the broader CE marked decision support indication, rather than the narrow United States triage clearance, is what is being deployednot SilverCloud by Amwell
- A radiology department building an AI governance programme that wants one vendor covering both chest radiograph and head CT rather than contracting two separate algorithm suppliersnot SilverCloud by Amwell
SilverCloud by Amwell
- An NHS talking therapies service needing a digital option that fits national reporting requirements and reduces waiting list pressure for step two interventionsnot Annalise.ai
- A health plan wanting a digital mental health offering it can defend to a clinical governance committee with peer reviewed trial evidencenot Annalise.ai
- A university counselling service facing demand it cannot staff, using guided digital cognitive behavioural therapy as a first stepnot Annalise.ai
- An employer that wants an evidence based clinical intervention rather than a wellbeing content librarynot Annalise.ai
Where each one falls short
Documented limitations, not opinions. Every one is a constraint you would hit in normal use.
Annalise.ai
- The United States cleared indication covers roughly ten findings for triage and notification, far fewer than the model reports, so a buyer who evaluates the full multi-finding output and then contracts in the United States gets a much narrower cleared use.
- Triage AI reprioritises a worklist but does not change clinical decisions on its own, so departments that do not redesign how urgent studies are picked up see no measurable improvement in time to treatment.
- Published validation is largely reader study evidence on detection of individual findings; prospective evidence of shorter time to treatment in routine emergency care is thin.
- The Annalise brand is being migrated under the Harrison.ai name for the critical care offering, which creates ambiguity in multi-year contracts about what product name is actually being supported.
- A high finding count raises the alert burden, and departments report that low prevalence findings generate false positives that erode radiologist trust unless the alerting thresholds are tuned locally.
SilverCloud by Amwell
- The evidence base is for the guided model, and organisations that deploy SilverCloud as unstaffed self service get the completion rates of unguided self help, which is not what the trials measured.
- Supporter capacity is normally the buyer responsibility rather than part of the licence, so the real cost includes trained staff time that does not appear on the software quote.
- Digital cognitive behavioural therapy has substantial dropout across all vendors, so a service planning capacity from enrolment numbers rather than completion numbers will overstate the throughput gained.
- It is now sold as part of the Amwell portfolio, and Amwell has restructured its product lines since acquiring SilverCloud, so buyers should ask how SilverCloud is positioned within the Amwell Converge platform and whether it can still be bought standalone.
- Guided digital cognitive behavioural therapy is a step two intervention and does not serve moderate to severe presentations, so a service that buys it without a funded escalation pathway simply relocates the queue.
Pricing, plan by plan
Annalise.ai
On request- Annalise Enterprise$undefined/year
- Priced per study analysed or as an annual volume subscription
- CXR and CTB licensed separately
- Cleared finding set differs by market, which changes what you are buying
SilverCloud by Amwell
On request- SilverCloud by Amwell$undefined/year
- Priced per member per month or per completed course depending on the buyer type
- Supporter capacity is usually provided by the buyer, not included in the licence
- Programme library scope affects the rate
Which should you pick?
Choose Annalise.ai if
- You need annalise enterprise cxr.
- You work on Web, Cloud, On-premise.
- You also want annalise enterprise ctb.
Choose SilverCloud by Amwell if
- You need guided programmes.
- You work on Web, iOS, Android.
- You also want supporter review.
Questions people ask
- Is Annalise.ai or SilverCloud by Amwell better?
- Neither clearly leads. Annalise.ai starts at On request and SilverCloud by Amwell at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
- Which is cheaper, Annalise.ai or SilverCloud by Amwell?
- Annalise.ai starts at On request and SilverCloud by Amwell at On request.
- Does Annalise.ai or SilverCloud by Amwell run on more platforms?
- Annalise.ai runs on Web, Cloud, On-premise. SilverCloud by Amwell runs on Web, iOS, Android.
- What is Annalise.ai best used for?
- Annalise.ai is most often used for an emergency department wanting pneumothorax and intracranial haemorrhage pushed to the front of the reading queue overnight when cover is thinnest, a teleradiology provider covering many small hospitals that needs consistent triage before a human reads, a screening programme in europe where the broader ce marked decision support indication, rather than the narrow united states triage clearance, is what is being deployed, a radiology department building an ai governance programme that wants one vendor covering both chest radiograph and head ct rather than contracting two separate algorithm suppliers. Of those, an emergency department wanting pneumothorax and intracranial haemorrhage pushed to the front of the reading queue overnight when cover is thinnest and a teleradiology provider covering many small hospitals that needs consistent triage before a human reads are not what SilverCloud by Amwell is typically brought in for.
- What can Annalise.ai do that SilverCloud by Amwell cannot?
- Annalise.ai covers Annalise Enterprise CXR, Annalise Enterprise CTB, Triage and notification, Worklist reprioritisation. SilverCloud by Amwell covers Guided programmes, Supporter review, Symptom measurement, Clinician dashboard.
Answered from the vendors’ own pages
Annalise.ai: How many findings are FDA cleared?
Around ten across chest X-ray and head CT, for triage and notification only. The model reports far more findings than that; the rest are not cleared in the United States.
SilverCloud by Amwell: Is SilverCloud still available under its own name?
Yes. It is marketed as SilverCloud by Amwell and has its own product pages and NHS partnership, though contracting runs through Amwell.
Annalise.ai: Is the European position different?
Yes. CE marking under the medical device regulation covers a broader decision support indication than the United States triage and notification clearances, so the same software is a different regulatory product depending on where you deploy it.
SilverCloud by Amwell: What evidence supports it?
It has been evaluated in independently led randomised controlled trials, including a National Institute of Mental Health funded study published in Nature Human Behaviour in 2026 examining prevalence of mental disorders over two years at scale.
Annalise.ai: Does it diagnose?
No. In the United States it is a triage and notification device: it flags studies for earlier review, and the radiologist makes the diagnosis.
SilverCloud by Amwell: Do we need to provide the supporters?
In most deployments, yes. The guided model requires trained supporter time, and that staffing is usually the buyer responsibility rather than included in the licence.
Annalise.ai: Is Annalise.ai becoming Harrison.ai?
The critical care offering is now marketed under the Harrison.ai name. Ask the vendor to name the contracted product explicitly before signing a multi-year deal.
SilverCloud by Amwell: Is it suitable for severe presentations?
No. It is a step two style intervention for mild to moderate presentations, and it needs a funded escalation pathway for anything more severe.
Related pages
More on Annalise.ai
More on SilverCloud by Amwell
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