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Healthcare · head to head

Paige vs SilverCloud by Amwell

Paige logo

Paige

Healthcare

Digital pathology AI holding the first FDA De Novo authorisation for a pathology algorithm, now part of Tempus

From
On request
Rated
-
Full reviewWebsite
SilverCloud by Amwell logo

SilverCloud by Amwell

Healthcare

Guided digital cognitive behavioural therapy with a published randomised trial evidence base

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: Paige the FDA authorisation is confined to prostate core needle biopsies, on compatible scanners, viewed through FullFocus, as an adjunct only; every other tissue type and every grading claim is outside that authorisation in the United States.; SilverCloud by Amwell the evidence base is for the guided model, and organisations that deploy SilverCloud as unstaffed self service get the completion rates of unguided self help, which is not what the trials measured.
  • They diverge on capability: Paige covers Paige Prostate Detect, SilverCloud by Amwell covers Guided programmes.
  • Prices and features above were last checked on 1 September 2026.

Where they differ

Only the attributes on which Paige and SilverCloud by Amwell actually diverge.

Attributes where Paige and SilverCloud by Amwell differ
AttributePaigeSilverCloud by Amwell
PlatformsWeb, Cloud, On-premiseWeb, iOS, Android

Identical on both: starting price (On request), pricing model (quote), free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Paige

  • Paige Prostate Detect
  • Paige Prostate Grade and Quantify
  • Perineural invasion detection
  • Breast and lymph node applications
  • FullFocus viewer
  • Foundation models
  • OmniScreen
  • Paige Alba

Only in SilverCloud by Amwell

  • Guided programmes
  • Supporter review
  • Symptom measurement
  • Clinician dashboard
  • Risk detection
  • NHS talking therapies alignment
  • Multiple deployment models

What people use each for

The jobs each tool is most often brought in to do.

Paige

  • A reference laboratory processing high volumes of prostate core needle biopsies where a second read on every case is not staffablenot SilverCloud by Amwell
  • A pathology department already digitised that wants a documented safety net against missed small foci of cancernot SilverCloud by Amwell
  • A hospital laboratory struggling to recruit uropathology subspecialists and needing consistency across generalist reportingnot SilverCloud by Amwell
  • A pharmaceutical company needing consistent biomarker scoring across trial sites rather than site-by-site pathologist variabilitynot SilverCloud by Amwell

SilverCloud by Amwell

  • An NHS talking therapies service needing a digital option that fits national reporting requirements and reduces waiting list pressure for step two interventionsnot Paige
  • A health plan wanting a digital mental health offering it can defend to a clinical governance committee with peer reviewed trial evidencenot Paige
  • A university counselling service facing demand it cannot staff, using guided digital cognitive behavioural therapy as a first stepnot Paige
  • An employer that wants an evidence based clinical intervention rather than a wellbeing content librarynot Paige

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Paige

  • The FDA authorisation is confined to prostate core needle biopsies, on compatible scanners, viewed through FullFocus, as an adjunct only; every other tissue type and every grading claim is outside that authorisation in the United States.
  • The algorithm is worthless without a digital pathology programme already running, and slide scanning, storage and workflow typically cost far more than the software licence.
  • Tempus acquired Paige in 2025, so the roadmap now competes for attention inside a genomics-led business, and the pathology-only buyer is no longer the primary customer.
  • Scanner compatibility is a hard constraint rather than a preference, and a laboratory with an unsupported scanner fleet cannot use the authorised indication at all.
  • Pricing is per case or per slide and unpublished, so a laboratory cannot model cost per reported case without entering a sales process.

SilverCloud by Amwell

  • The evidence base is for the guided model, and organisations that deploy SilverCloud as unstaffed self service get the completion rates of unguided self help, which is not what the trials measured.
  • Supporter capacity is normally the buyer responsibility rather than part of the licence, so the real cost includes trained staff time that does not appear on the software quote.
  • Digital cognitive behavioural therapy has substantial dropout across all vendors, so a service planning capacity from enrolment numbers rather than completion numbers will overstate the throughput gained.
  • It is now sold as part of the Amwell portfolio, and Amwell has restructured its product lines since acquiring SilverCloud, so buyers should ask how SilverCloud is positioned within the Amwell Converge platform and whether it can still be bought standalone.
  • Guided digital cognitive behavioural therapy is a step two intervention and does not serve moderate to severe presentations, so a service that buys it without a funded escalation pathway simply relocates the queue.

Pricing, plan by plan

Paige

On request
  • Paige clinical applications$undefined/year
    • Priced per case or per slide analysed under annual agreement
    • Prostate, breast and other applications licensed separately
    • Requires compatible whole slide scanner and the FullFocus viewer for the authorised indication

SilverCloud by Amwell

On request
  • SilverCloud by Amwell$undefined/year
    • Priced per member per month or per completed course depending on the buyer type
    • Supporter capacity is usually provided by the buyer, not included in the licence
    • Programme library scope affects the rate

Which should you pick?

Choose Paige if

  • You need paige prostate detect.
  • You work on Web, Cloud, On-premise.
  • You also want paige prostate grade and quantify.
Paige review

Choose SilverCloud by Amwell if

  • You need guided programmes.
  • You work on Web, iOS, Android.
  • You also want supporter review.
SilverCloud by Amwell review

Questions people ask

Is Paige or SilverCloud by Amwell better?
Neither clearly leads. Paige starts at On request and SilverCloud by Amwell at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Paige or SilverCloud by Amwell?
Paige starts at On request and SilverCloud by Amwell at On request.
Does Paige or SilverCloud by Amwell run on more platforms?
Paige runs on Web, Cloud, On-premise. SilverCloud by Amwell runs on Web, iOS, Android.
What is Paige best used for?
Paige is most often used for a reference laboratory processing high volumes of prostate core needle biopsies where a second read on every case is not staffable, a pathology department already digitised that wants a documented safety net against missed small foci of cancer, a hospital laboratory struggling to recruit uropathology subspecialists and needing consistency across generalist reporting, a pharmaceutical company needing consistent biomarker scoring across trial sites rather than site-by-site pathologist variability. Of those, a reference laboratory processing high volumes of prostate core needle biopsies where a second read on every case is not staffable and a pathology department already digitised that wants a documented safety net against missed small foci of cancer are not what SilverCloud by Amwell is typically brought in for.
What can Paige do that SilverCloud by Amwell cannot?
Paige covers Paige Prostate Detect, Paige Prostate Grade and Quantify, Perineural invasion detection, Breast and lymph node applications. SilverCloud by Amwell covers Guided programmes, Supporter review, Symptom measurement, Clinician dashboard.

Answered from the vendors’ own pages

Paige: What exactly is FDA authorised?

Paige Prostate Detect, as an adjunct for identifying areas of interest on digitised prostate core needle biopsy slides, viewed through the Paige FullFocus viewer on a compatible scanner. Nothing else in the portfolio holds that authorisation in the United States.

SilverCloud by Amwell: Is SilverCloud still available under its own name?

Yes. It is marketed as SilverCloud by Amwell and has its own product pages and NHS partnership, though contracting runs through Amwell.

Paige: Is the European position broader?

Yes. The Paige Prostate suite including grading and quantification received IVDR certification in 2025, which covers more than the United States authorisation.

SilverCloud by Amwell: What evidence supports it?

It has been evaluated in independently led randomised controlled trials, including a National Institute of Mental Health funded study published in Nature Human Behaviour in 2026 examining prevalence of mental disorders over two years at scale.

Paige: What did the pivotal study measure?

Pathologist cancer detection on individual slide images improved, with reported reductions in false negative and false positive readings. It measured pathologist performance with the tool, not standalone algorithm accuracy.

SilverCloud by Amwell: Do we need to provide the supporters?

In most deployments, yes. The guided model requires trained supporter time, and that staffing is usually the buyer responsibility rather than included in the licence.

Paige: Who owns Paige now?

Tempus AI acquired Paige in 2025. Products remain branded Paige.

SilverCloud by Amwell: Is it suitable for severe presentations?

No. It is a step two style intervention for mild to moderate presentations, and it needs a funded escalation pathway for anything more severe.

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