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Healthcare · head to head

Signant Health vs TherapyNotes

Signant Health logo

Signant Health

Healthcare

eCOA-first clinical trial platform that has grown outward into EDC, eConsent and televisits

From
On request
Rated
-
TherapyNotes logo

TherapyNotes

Healthcare

EHR and practice management for therapists

From
$39/month
Rated
-

The short version

  • Each has a real cost: Signant Health no pricing is published, and the software licence is a minority of the real bill once instrument licensing, translations, device provisioning and services are added, so early budget estimates are routinely too low.; TherapyNotes no API access, preventing integration with external systems
  • They diverge on capability: Signant Health covers eCOA and ePRO, TherapyNotes covers Electronic Health Records.
  • Prices and features above were last checked on 31 August 2026.

Where they differ

Only the attributes on which Signant Health and TherapyNotes actually diverge.

Attributes where Signant Health and TherapyNotes differ
AttributeSignant HealthTherapyNotes
Starting priceOn request$39/month
Pricing modelquotesubscription
PlatformsWeb, iOS, AndroidWeb
FoundedUnknown2010

Identical on both: free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Signant Health

  • eCOA and ePRO
  • Unified platform
  • eConsent
  • Randomisation and supplies
  • TeleVisits
  • Rater training
  • Data surveillance
  • Instrument library

Only in TherapyNotes

  • Electronic Health Records
  • Scheduling
  • Billing
  • Patient Portal
  • Telehealth
  • Outcome Tracking
  • Clearinghouses
  • Insurance

What people use each for

The jobs each tool is most often brought in to do.

Signant Health

  • A central nervous system or psychiatry trial where the primary endpoint is a rated scale and rater consistency decides the readoutnot TherapyNotes
  • A global study needing an outcome instrument translated and linguistically validated across a dozen languagesnot TherapyNotes
  • A decentralised or hybrid protocol combining televisits, eConsent and at-home patient reported outcomesnot TherapyNotes
  • A sponsor consolidating separate eCOA, eConsent and randomisation vendors onto one platform to cut reconciliation worknot TherapyNotes

TherapyNotes

  • Patient Carenot Signant Health
  • Medical Recordsnot Signant Health
  • Practice Managementnot Signant Health
  • Telehealthnot Signant Health

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Signant Health

  • No pricing is published, and the software licence is a minority of the real bill once instrument licensing, translations, device provisioning and services are added, so early budget estimates are routinely too low.
  • Linguistic validation is charged per instrument per language and is on the critical path to first patient in, so adding a country late in start-up produces both a cost and a schedule hit.
  • Provisioned participant devices bring logistics, replacement, shipping and cellular connectivity obligations that persist for the life of the trial and are frequently underestimated.
  • The EDC component is newer than the eCOA heritage, so sponsors with complex data management requirements often keep an incumbent EDC and lose the single-database benefit that justifies the platform.
  • It is priced and scoped for sponsor-grade trials, which makes it a poor fit for investigator-initiated or academic studies that need outcome collection without the services layer.

TherapyNotes

  • No API access, preventing integration with external systems
  • Outdated interface compared to AI-driven competitors
  • No native mobile app for iOS or Android
  • No bulk actions to update multiple sessions at once

Pricing, plan by plan

Signant Health

On request
  • SmartSignals Unified Platform$undefined/year
    • Priced per study through a sales process
    • Modules selected per protocol: EDC, eCOA, randomisation, eConsent, TeleVisits
    • Instrument licensing paid to scale owners on top of platform cost

TherapyNotes

$39/month
  • Solo$39/month
    • Full EHR
    • Scheduling
    • Patient portal

Which should you pick?

Choose Signant Health if

  • You need ecoa and epro.
  • You work on Web, iOS, Android.
  • You also want unified platform.

Choose TherapyNotes if

  • You need electronic health records.
  • You also want scheduling.

Questions people ask

Is Signant Health or TherapyNotes better?
Neither clearly leads. Signant Health starts at On request and TherapyNotes at $39/month, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Signant Health or TherapyNotes?
Signant Health starts at On request and TherapyNotes at $39/month.
Does Signant Health or TherapyNotes run on more platforms?
Signant Health runs on Web, iOS, Android. TherapyNotes runs on Web.
What is Signant Health best used for?
Signant Health is most often used for a central nervous system or psychiatry trial where the primary endpoint is a rated scale and rater consistency decides the readout, a global study needing an outcome instrument translated and linguistically validated across a dozen languages, a decentralised or hybrid protocol combining televisits, econsent and at-home patient reported outcomes, a sponsor consolidating separate ecoa, econsent and randomisation vendors onto one platform to cut reconciliation work. Of those, a central nervous system or psychiatry trial where the primary endpoint is a rated scale and rater consistency decides the readout and a global study needing an outcome instrument translated and linguistically validated across a dozen languages are not what TherapyNotes is typically brought in for.
What can Signant Health do that TherapyNotes cannot?
Signant Health covers eCOA and ePRO, Unified platform, eConsent, Randomisation and supplies. TherapyNotes covers Electronic Health Records, Scheduling, Billing, Patient Portal.

Answered from the vendors’ own pages

Signant Health: What is Signant best at?

Electronic clinical outcome assessment, particularly rated scales in central nervous system and psychiatry trials, together with rater training and endpoint quality services.

TherapyNotes: Does TherapyNotes integrate with other applications?

TherapyNotes has zero API availability and cannot connect to external systems including marketing platforms, CRMs, or data dashboards. Unlike competitors, it lacks integration capabilities.

Source
Signant Health: Is pricing published?

No. Everything is quoted per study, and instrument licences, translations and devices sit on top of the platform cost.

TherapyNotes: What are TherapyNotes pricing plans?

TherapyNotes charges $69/month for a solo practitioner plan and $79/month for the first clinician in a group with $50/month per additional clinician. A 30-day free trial is included with every plan.

Source
Signant Health: Can I use it only for eCOA?

Yes. The modules are selected per protocol, and many sponsors take eCOA and eConsent while keeping an existing EDC.

TherapyNotes: Does TherapyNotes include telehealth?

Yes. TherapyNotes includes Basic Telehealth at no extra cost on every plan, with standard-definition video for up to 2 participants. Premium Telehealth with full HD, screen sharing, and closed captions costs $15 per clinician per month.

Source
Signant Health: What drives the timeline?

Translation and linguistic validation of outcome instruments, which is per language per instrument and sits on the critical path to study start.

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