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Healthcare · head to head

Paige vs SimplePractice

Paige logo

Paige

Healthcare

Digital pathology AI holding the first FDA De Novo authorisation for a pathology algorithm, now part of Tempus

From
On request
Rated
-
SimplePractice logo

SimplePractice

Healthcare

Practice management and EHR for mental health and therapy

From
$49/month
Rated
-

The short version

  • Each has a real cost: Paige the FDA authorisation is confined to prostate core needle biopsies, on compatible scanners, viewed through FullFocus, as an adjunct only; every other tissue type and every grading claim is outside that authorisation in the United States.; SimplePractice no API or webhook support for integrations, preventing connections to Zapier or custom automation tools
  • They diverge on capability: Paige covers Paige Prostate Detect, SimplePractice covers Scheduling.
  • Prices and features above were last checked on 1 September 2026.

Where they differ

Only the attributes on which Paige and SimplePractice actually diverge.

Attributes where Paige and SimplePractice differ
AttributePaigeSimplePractice
Starting priceOn request$49/month
Pricing modelquoteUnknown
PlatformsWeb, Cloud, On-premiseWeb, iOS, Android
FoundedUnknown2011

Identical on both: free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Paige

  • Paige Prostate Detect
  • Paige Prostate Grade and Quantify
  • Perineural invasion detection
  • Breast and lymph node applications
  • FullFocus viewer
  • Foundation models
  • OmniScreen
  • Paige Alba

Only in SimplePractice

  • Scheduling
  • Client Portal
  • Notes
  • Billing
  • Telehealth
  • Documents
  • Stripe
  • PayPal

What people use each for

The jobs each tool is most often brought in to do.

Paige

  • A reference laboratory processing high volumes of prostate core needle biopsies where a second read on every case is not staffablenot SimplePractice
  • A pathology department already digitised that wants a documented safety net against missed small foci of cancernot SimplePractice
  • A hospital laboratory struggling to recruit uropathology subspecialists and needing consistency across generalist reportingnot SimplePractice
  • A pharmaceutical company needing consistent biomarker scoring across trial sites rather than site-by-site pathologist variabilitynot SimplePractice

SimplePractice

  • Patient Carenot Paige
  • Medical Recordsnot Paige
  • Practice Managementnot Paige
  • Telehealthnot Paige

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Paige

  • The FDA authorisation is confined to prostate core needle biopsies, on compatible scanners, viewed through FullFocus, as an adjunct only; every other tissue type and every grading claim is outside that authorisation in the United States.
  • The algorithm is worthless without a digital pathology programme already running, and slide scanning, storage and workflow typically cost far more than the software licence.
  • Tempus acquired Paige in 2025, so the roadmap now competes for attention inside a genomics-led business, and the pathology-only buyer is no longer the primary customer.
  • Scanner compatibility is a hard constraint rather than a preference, and a laboratory with an unsupported scanner fleet cannot use the authorised indication at all.
  • Pricing is per case or per slide and unpublished, so a laboratory cannot model cost per reported case without entering a sales process.

SimplePractice

  • No API or webhook support for integrations, preventing connections to Zapier or custom automation tools
  • Lacks AI clinical documentation in base plan, requiring manual note typing which takes 15-30 minutes per session
  • Reporting and customization features are limited compared to competitors, with weak insurance workflow support
  • Hidden costs beyond base pricing, with real cost often 3x higher after add-ons and annual increases
  • Telehealth component reported as unstable and frequently unreliable by some users

Pricing, plan by plan

Paige

On request
  • Paige clinical applications$undefined/year
    • Priced per case or per slide analysed under annual agreement
    • Prostate, breast and other applications licensed separately
    • Requires compatible whole slide scanner and the FullFocus viewer for the authorised indication

SimplePractice

$49/month
  • Starter$49/month
    • Scheduling
    • Documentation
    • Client portal
  • Essential$79/month
    • Billing and payments
    • Insurance claim filing
    • Telehealth
  • Plus$99/month
    • Website builder
    • Advanced reporting
    • ePrescribe integration

Which should you pick?

Choose Paige if

  • You need paige prostate detect.
  • You work on Web, Cloud, On-premise.
  • You also want paige prostate grade and quantify.

Choose SimplePractice if

  • You need scheduling.
  • You work on Web, iOS, Android.
  • You also want client portal.

Questions people ask

Is Paige or SimplePractice better?
Neither clearly leads. Paige starts at On request and SimplePractice at $49/month, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Paige or SimplePractice?
Paige starts at On request and SimplePractice at $49/month.
Does Paige or SimplePractice run on more platforms?
Paige runs on Web, Cloud, On-premise. SimplePractice runs on Web, iOS, Android.
What is Paige best used for?
Paige is most often used for a reference laboratory processing high volumes of prostate core needle biopsies where a second read on every case is not staffable, a pathology department already digitised that wants a documented safety net against missed small foci of cancer, a hospital laboratory struggling to recruit uropathology subspecialists and needing consistency across generalist reporting, a pharmaceutical company needing consistent biomarker scoring across trial sites rather than site-by-site pathologist variability. Of those, a reference laboratory processing high volumes of prostate core needle biopsies where a second read on every case is not staffable and a pathology department already digitised that wants a documented safety net against missed small foci of cancer are not what SimplePractice is typically brought in for.
What can Paige do that SimplePractice cannot?
Paige covers Paige Prostate Detect, Paige Prostate Grade and Quantify, Perineural invasion detection, Breast and lymph node applications. SimplePractice covers Scheduling, Client Portal, Notes, Billing.

Answered from the vendors’ own pages

Paige: What exactly is FDA authorised?

Paige Prostate Detect, as an adjunct for identifying areas of interest on digitised prostate core needle biopsy slides, viewed through the Paige FullFocus viewer on a compatible scanner. Nothing else in the portfolio holds that authorisation in the United States.

SimplePractice: What does SimplePractice pricing include?

SimplePractice tiers start at $49 (Starter), $79 (Essential), and $99 (Plus) per clinician per month. Add-ons cost extra, including AI Note Taker at $35/month and ePrescribe at $49/month plus $89 setup.

Source
Paige: Is the European position broader?

Yes. The Paige Prostate suite including grading and quantification received IVDR certification in 2025, which covers more than the United States authorisation.

SimplePractice: Does SimplePractice include telehealth?

Yes, all SimplePractice tiers include HIPAA-compliant integrated telehealth, allowing therapists to conduct secure video sessions directly from the platform.

Source
Paige: What did the pivotal study measure?

Pathologist cancer detection on individual slide images improved, with reported reductions in false negative and false positive readings. It measured pathologist performance with the tool, not standalone algorithm accuracy.

SimplePractice: Is AI documentation included in SimplePractice?

No, AI clinical notes are not included in base pricing. SimplePractice offers an optional AI Note Taker add-on for $35/month that provides basic transcription, though it lacks advanced note generation features of competitors.

Source
Paige: Who owns Paige now?

Tempus AI acquired Paige in 2025. Products remain branded Paige.

SimplePractice: Does SimplePractice support international or non-US workflows?

No, SimplePractice is designed for US practices only and does not support non-US workflows, insurance structures, or currencies, limiting its use for international practitioners.

Source
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