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Healthcare · head to head

athenaOne vs PathAI

athenaOne logo

athenaOne

Healthcare

Unified cloud platform combining EHR, practice management, and patient engagement

From
$250/month
Rated
-
Full reviewWebsite
PathAI logo

PathAI

Healthcare

Digital pathology image management with an FDA cleared platform for primary diagnosis

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: athenaOne no published pricing on homepage, pricing available through request for demo only; PathAI aISight is labelled research use only and cannot be used for primary diagnosis; only AISight Dx carries the FDA clearance and CE-IVD mark, and laboratories regularly buy the wrong configuration and discover they cannot sign out on it.
  • They diverge on capability: athenaOne covers Electronic Health Records, PathAI covers AISight image management.
  • Prices and features above were last checked on 1 September 2026.

Where they differ

Only the attributes on which athenaOne and PathAI actually diverge.

Attributes where athenaOne and PathAI differ
AttributeathenaOnePathAI
Starting price$250/monthOn request
Pricing modelsubscriptionquote
PlatformsWeb, Mobile, ApiWeb
Founded1997Unknown

Identical on both: free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in athenaOne

  • Electronic Health Records
  • Practice Management
  • Patient Engagement
  • Care Coordination
  • Analytics
  • Mobile App
  • Telehealth
  • Labs

Only in PathAI

  • AISight image management
  • AISight Dx
  • Scanner interoperability
  • Case and worklist management
  • AI algorithm deployment
  • Biopharmaceutical research tooling
  • LIS integration

What people use each for

The jobs each tool is most often brought in to do.

athenaOne

  • Patient Carenot PathAI
  • Medical Recordsnot PathAI
  • Practice Managementnot PathAI
  • Telehealthnot PathAI

PathAI

  • An academic medical centre going digital for primary diagnosis that needs the FDA cleared AISight Dx configuration rather than the research labelled versionnot athenaOne
  • A reference laboratory consolidating subspecialty sign out across sites so a specialist pathologist can read cases from any locationnot athenaOne
  • A pharmaceutical company needing consistent quantitative scoring of trial biopsies across many sites and readersnot athenaOne
  • A laboratory with a mixed scanner estate that needs one image management layer rather than each scanner vendor viewernot athenaOne

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

athenaOne

  • No published pricing on homepage, pricing available through request for demo only
  • Healthcare EHR systems typically require enterprise-level contracts

PathAI

  • AISight is labelled research use only and cannot be used for primary diagnosis; only AISight Dx carries the FDA clearance and CE-IVD mark, and laboratories regularly buy the wrong configuration and discover they cannot sign out on it.
  • The software licence is usually the smallest line in a digital pathology project, behind scanners, storage and network capacity, so a business case built around the software cost understates the real investment by a wide margin.
  • Whole slide images are very large, so a laboratory that does not model storage growth and retention policy from the start faces storage costs that grow faster than case volume and dominate the renewal.
  • Clinical validation is required per subspecialty rather than once for the platform, which means dermatopathology, gastrointestinal and breast each need their own concordance study and pathologist time before go live.
  • PathAI competes against pathology incumbents that also sell the scanners, and a laboratory buying an independent image management layer takes on the integration risk between scanner vendor and software vendor itself.

Pricing, plan by plan

athenaOne

$250/month

No published plan breakdown. See the athenaOne review.

PathAI

On request
  • AISight$undefined/year
    • Priced by annual slide or case volume and by pathologist seats
    • AISight Dx, the clinically cleared configuration, quoted separately from research use AISight
    • Image storage priced by capacity and retention policy

Which should you pick?

Choose athenaOne if

  • You need electronic health records.
  • You work on Web, Mobile, Api.
  • You also want practice management.
athenaOne review

Choose PathAI if

  • You need aisight image management.
  • You also want aisight dx.
PathAI review

Questions people ask

Is athenaOne or PathAI better?
Neither clearly leads. athenaOne starts at $250/month and PathAI at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, athenaOne or PathAI?
athenaOne starts at $250/month and PathAI at On request.
Does athenaOne or PathAI run on more platforms?
athenaOne runs on Web, Mobile, Api. PathAI runs on Web.
What is athenaOne best used for?
athenaOne is most often used for patient care, medical records, practice management, telehealth. Of those, patient care and medical records are not what PathAI is typically brought in for.
What can athenaOne do that PathAI cannot?
athenaOne covers Electronic Health Records, Practice Management, Patient Engagement, Care Coordination. PathAI covers AISight image management, AISight Dx, Scanner interoperability, Case and worklist management.

Answered from the vendors’ own pages

athenaOne: What does athenaOne cost?

athenaOne does not publish pricing on their website. Organizations must contact their sales team or schedule a demo to receive a customized quote based on practice size, specialty, and required features.

Source
PathAI: What is the difference between AISight and AISight Dx?

AISight is for research use only and not for clinical diagnostic use. AISight Dx received FDA 510(k) clearance in June 2025 for primary diagnosis and is CE-IVD marked in the EEA, UK and Switzerland. Only the Dx configuration can be used to sign out cases.

PathAI: Can we use our existing scanners?

Yes. AISight is designed to ingest images from multiple whole slide scanner vendors, which is one of the main reasons laboratories choose an independent image management layer.

PathAI: Do the AI algorithms carry the same clearance as the platform?

No. The platform clearance covers image management for primary diagnosis. Individual algorithms have their own labelling, and many are research use only. Check each one separately.

PathAI: Is pricing published?

No. It is quoted by slide or case volume, pathologist seats and storage, with the clinically cleared configuration priced separately.

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