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Healthcare · head to head

eClinicalWorks Prime vs PathAI

eClinicalWorks Prime logo

eClinicalWorks Prime

Healthcare

AI-powered cloud EHR for modern healthcare practices

From
$180/month
Rated
-
Full reviewWebsite
PathAI logo

PathAI

Healthcare

Digital pathology image management with an FDA cleared platform for primary diagnosis

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: eClinicalWorks Prime eHR Only is $449/month per provider and EHR with Practice Management is $599/month per provider, priced per provider rather than a flat practice fee; PathAI aISight is labelled research use only and cannot be used for primary diagnosis; only AISight Dx carries the FDA clearance and CE-IVD mark, and laboratories regularly buy the wrong configuration and discover they cannot sign out on it.
  • They diverge on capability: eClinicalWorks Prime covers Electronic Health Records, PathAI covers AISight image management.
  • Prices and features above were last checked on 1 September 2026.

Where they differ

Only the attributes on which eClinicalWorks Prime and PathAI actually diverge.

Attributes where eClinicalWorks Prime and PathAI differ
AttributeeClinicalWorks PrimePathAI
Starting price$180/monthOn request
Pricing modelsubscriptionquote
PlatformsWeb, Mobile, ApiWeb
Founded1999Unknown

Identical on both: free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in eClinicalWorks Prime

  • Electronic Health Records
  • AI-Assisted Documentation
  • Practice Management
  • Revenue Cycle
  • Patient Portal
  • Voice Recognition
  • Telehealth
  • HL7

Only in PathAI

  • AISight image management
  • AISight Dx
  • Scanner interoperability
  • Case and worklist management
  • AI algorithm deployment
  • Biopharmaceutical research tooling
  • LIS integration

What people use each for

The jobs each tool is most often brought in to do.

eClinicalWorks Prime

  • Small to mid-size practices (1-9 providers) wanting per-provider EHR pricing with included trainingnot PathAI

PathAI

  • An academic medical centre going digital for primary diagnosis that needs the FDA cleared AISight Dx configuration rather than the research labelled versionnot eClinicalWorks Prime
  • A reference laboratory consolidating subspecialty sign out across sites so a specialist pathologist can read cases from any locationnot eClinicalWorks Prime
  • A pharmaceutical company needing consistent quantitative scoring of trial biopsies across many sites and readersnot eClinicalWorks Prime
  • A laboratory with a mixed scanner estate that needs one image management layer rather than each scanner vendor viewernot eClinicalWorks Prime

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

eClinicalWorks Prime

  • EHR Only is $449/month per provider and EHR with Practice Management is $599/month per provider, priced per provider rather than a flat practice fee
  • The RCM as a Service option charges 2.9% of practice collections rather than a fixed fee
  • Practices with more than 9 providers are charged additional implementation fees beyond the included training

PathAI

  • AISight is labelled research use only and cannot be used for primary diagnosis; only AISight Dx carries the FDA clearance and CE-IVD mark, and laboratories regularly buy the wrong configuration and discover they cannot sign out on it.
  • The software licence is usually the smallest line in a digital pathology project, behind scanners, storage and network capacity, so a business case built around the software cost understates the real investment by a wide margin.
  • Whole slide images are very large, so a laboratory that does not model storage growth and retention policy from the start faces storage costs that grow faster than case volume and dominate the renewal.
  • Clinical validation is required per subspecialty rather than once for the platform, which means dermatopathology, gastrointestinal and breast each need their own concordance study and pathologist time before go live.
  • PathAI competes against pathology incumbents that also sell the scanners, and a laboratory buying an independent image management layer takes on the integration risk between scanner vendor and software vendor itself.

Pricing, plan by plan

eClinicalWorks Prime

$180/month

No published plan breakdown. See the eClinicalWorks Prime review.

PathAI

On request
  • AISight$undefined/year
    • Priced by annual slide or case volume and by pathologist seats
    • AISight Dx, the clinically cleared configuration, quoted separately from research use AISight
    • Image storage priced by capacity and retention policy

Which should you pick?

Choose eClinicalWorks Prime if

  • You need electronic health records.
  • You work on Web, Mobile, Api.
  • You also want ai-assisted documentation.
eClinicalWorks Prime review

Choose PathAI if

  • You need aisight image management.
  • You also want aisight dx.
PathAI review

Questions people ask

Is eClinicalWorks Prime or PathAI better?
Neither clearly leads. eClinicalWorks Prime starts at $180/month and PathAI at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, eClinicalWorks Prime or PathAI?
eClinicalWorks Prime starts at $180/month and PathAI at On request.
Does eClinicalWorks Prime or PathAI run on more platforms?
eClinicalWorks Prime runs on Web, Mobile, Api. PathAI runs on Web.
What is eClinicalWorks Prime best used for?
eClinicalWorks Prime is most often used for small to mid-size practices (1-9 providers) wanting per-provider ehr pricing with included training. Of those, small to mid-size practices (1-9 providers) wanting per-provider ehr pricing with included training is not what PathAI is typically brought in for.
What can eClinicalWorks Prime do that PathAI cannot?
eClinicalWorks Prime covers Electronic Health Records, AI-Assisted Documentation, Practice Management, Revenue Cycle. PathAI covers AISight image management, AISight Dx, Scanner interoperability, Case and worklist management.

Answered from the vendors’ own pages

eClinicalWorks Prime: How much does eClinicalWorks Prime cost?

eClinicalWorks does not publish pricing for its Prime RCM (Revenue Cycle Management) service. The vendor positions it as 'Better RCM service at a lower price than your current provider' but requires interested organizations to schedule a demo or contact sales at 508-836-2700 for custom pricing based on organizational size and specific requirements.

Source
PathAI: What is the difference between AISight and AISight Dx?

AISight is for research use only and not for clinical diagnostic use. AISight Dx received FDA 510(k) clearance in June 2025 for primary diagnosis and is CE-IVD marked in the EEA, UK and Switzerland. Only the Dx configuration can be used to sign out cases.

eClinicalWorks Prime: How can you get eClinicalWorks Prime pricing?

Contact eClinicalWorks directly at 508-836-2700 to speak with their sales team or schedule a demo to discuss pricing tailored to your organization.

Source
PathAI: Can we use our existing scanners?

Yes. AISight is designed to ingest images from multiple whole slide scanner vendors, which is one of the main reasons laboratories choose an independent image management layer.

PathAI: Do the AI algorithms carry the same clearance as the platform?

No. The platform clearance covers image management for primary diagnosis. Individual algorithms have their own labelling, and many are research use only. Check each one separately.

PathAI: Is pricing published?

No. It is quoted by slide or case volume, pathologist seats and storage, with the clinically cleared configuration priced separately.

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