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Healthcare · head to head

Kareo Clinical vs PathAI

Kareo Clinical logo

Kareo Clinical

Healthcare

Specialized EHR and practice management for independent and small practices

From
$89/month
Rated
-
PathAI logo

PathAI

Healthcare

Digital pathology image management with an FDA cleared platform for primary diagnosis

From
On request
Rated
-

The short version

  • Each has a real cost: Kareo Clinical kareo is now part of Tebra and sold under the Tebra brand rather than as a standalone product; PathAI aISight is labelled research use only and cannot be used for primary diagnosis; only AISight Dx carries the FDA clearance and CE-IVD mark, and laboratories regularly buy the wrong configuration and discover they cannot sign out on it.
  • They diverge on capability: Kareo Clinical covers Electronic Health Records, PathAI covers AISight image management.
  • Prices and features above were last checked on 1 September 2026.

Where they differ

Only the attributes on which Kareo Clinical and PathAI actually diverge.

Attributes where Kareo Clinical and PathAI differ
AttributeKareo ClinicalPathAI
Starting price$89/monthOn request
Pricing modelsubscriptionquote
PlatformsWeb, MobileWeb
Founded2010Unknown

Identical on both: free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Kareo Clinical

  • Electronic Health Records
  • Scheduling
  • Patient Portal
  • Medical Billing
  • ePrescribing
  • Analytics
  • Labs
  • Pharmacies

Only in PathAI

  • AISight image management
  • AISight Dx
  • Scanner interoperability
  • Case and worklist management
  • AI algorithm deployment
  • Biopharmaceutical research tooling
  • LIS integration

What people use each for

The jobs each tool is most often brought in to do.

Kareo Clinical

  • Practice management, scheduling and billing for independent medical practicesnot PathAI
  • Electronic health records and e-prescribing for small clinicsnot PathAI
  • Insurance claim submission and patient payment collectionnot PathAI

PathAI

  • An academic medical centre going digital for primary diagnosis that needs the FDA cleared AISight Dx configuration rather than the research labelled versionnot Kareo Clinical
  • A reference laboratory consolidating subspecialty sign out across sites so a specialist pathologist can read cases from any locationnot Kareo Clinical
  • A pharmaceutical company needing consistent quantitative scoring of trial biopsies across many sites and readersnot Kareo Clinical
  • A laboratory with a mixed scanner estate that needs one image management layer rather than each scanner vendor viewernot Kareo Clinical

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Kareo Clinical

  • Kareo is now part of Tebra and sold under the Tebra brand rather than as a standalone product
  • Tebra publishes no rate: pricing varies with provider count, features and implementation requirements and is quoted during a demo
  • Billing counts clinical providers such as MDs, DOs, NPs and PAs, so adding a prescriber raises the bill even though non clinical staff are free
  • Electronic prescribing of controlled substances setup costs about $75 per provider as a one time fee
  • PDMP integration costs $500 one time per facility plus about $50 per user per year

PathAI

  • AISight is labelled research use only and cannot be used for primary diagnosis; only AISight Dx carries the FDA clearance and CE-IVD mark, and laboratories regularly buy the wrong configuration and discover they cannot sign out on it.
  • The software licence is usually the smallest line in a digital pathology project, behind scanners, storage and network capacity, so a business case built around the software cost understates the real investment by a wide margin.
  • Whole slide images are very large, so a laboratory that does not model storage growth and retention policy from the start faces storage costs that grow faster than case volume and dominate the renewal.
  • Clinical validation is required per subspecialty rather than once for the platform, which means dermatopathology, gastrointestinal and breast each need their own concordance study and pathologist time before go live.
  • PathAI competes against pathology incumbents that also sell the scanners, and a laboratory buying an independent image management layer takes on the integration risk between scanner vendor and software vendor itself.

Pricing, plan by plan

Kareo Clinical

$89/month
  • Clinical Starter$89/month
    • EHR
    • Scheduling
    • Patient Portal
  • Clinical Plus$189/month
    • Everything in Starter
    • Billing
    • Analytics

PathAI

On request
  • AISight$undefined/year
    • Priced by annual slide or case volume and by pathologist seats
    • AISight Dx, the clinically cleared configuration, quoted separately from research use AISight
    • Image storage priced by capacity and retention policy

Which should you pick?

Choose Kareo Clinical if

  • You need electronic health records.
  • You work on Web, Mobile.
  • You also want scheduling.

Choose PathAI if

  • You need aisight image management.
  • You also want aisight dx.

Questions people ask

Is Kareo Clinical or PathAI better?
Neither clearly leads. Kareo Clinical starts at $89/month and PathAI at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Kareo Clinical or PathAI?
Kareo Clinical starts at $89/month and PathAI at On request.
Does Kareo Clinical or PathAI run on more platforms?
Kareo Clinical runs on Web, Mobile. PathAI runs on Web.
What is Kareo Clinical best used for?
Kareo Clinical is most often used for practice management, scheduling and billing for independent medical practices, electronic health records and e-prescribing for small clinics, insurance claim submission and patient payment collection. Of those, practice management, scheduling and billing for independent medical practices and electronic health records and e-prescribing for small clinics are not what PathAI is typically brought in for.
What can Kareo Clinical do that PathAI cannot?
Kareo Clinical covers Electronic Health Records, Scheduling, Patient Portal, Medical Billing. PathAI covers AISight image management, AISight Dx, Scanner interoperability, Case and worklist management.

Answered from the vendors’ own pages

Kareo Clinical: How much does Kareo Clinical (now Tebra) cost?

Kareo Clinical pricing is not published publicly. Pricing is based on the number of clinical providers in your practice, not seat licenses. Setup includes optional EPCS at $75/provider and PDMP Integration at $500 one-time per facility plus $50/user/year.

Source
PathAI: What is the difference between AISight and AISight Dx?

AISight is for research use only and not for clinical diagnostic use. AISight Dx received FDA 510(k) clearance in June 2025 for primary diagnosis and is CE-IVD marked in the EEA, UK and Switzerland. Only the Dx configuration can be used to sign out cases.

Kareo Clinical: Does Tebra charge for front desk staff and medical assistants?

No. Tebra provides unlimited non-clinical staff access at no extra cost. Front desk staff, medical assistants, billers, and office admins can all access scheduling, charting, and claims modules without increasing billing.

Source
PathAI: Can we use our existing scanners?

Yes. AISight is designed to ingest images from multiple whole slide scanner vendors, which is one of the main reasons laboratories choose an independent image management layer.

Kareo Clinical: Are there reduced rates for low-volume practices on Tebra?

Yes. Practices with providers billing under 100 claims monthly receive lower-tier pricing for those low-volume providers.

Source
PathAI: Do the AI algorithms carry the same clearance as the platform?

No. The platform clearance covers image management for primary diagnosis. Individual algorithms have their own labelling, and many are research use only. Check each one separately.

PathAI: Is pricing published?

No. It is quoted by slide or case volume, pathologist seats and storage, with the clinically cleared configuration priced separately.

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