Softwr

Healthcare · head to head

Annalise.ai vs Lyra Health

Annalise.ai logo

Annalise.ai

Healthcare

Multi-finding chest X-ray and head CT triage AI with FDA clearance on named findings, not on the whole model

From
On request
Rated
-
Full reviewWebsite
Lyra Health logo

Lyra Health

Healthcare

Employer purchased mental health benefit with a curated provider network and measurement based care

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: Annalise.ai the United States cleared indication covers roughly ten findings for triage and notification, far fewer than the model reports, so a buyer who evaluates the full multi-finding output and then contracts in the United States gets a much narrower cleared use.; Lyra Health covered sessions per member per year are set in the employer contract and vary widely between clients, so employees at two companies both using Lyra can receive very different benefits and the number is never published.
  • They diverge on capability: Annalise.ai covers Annalise Enterprise CXR, Lyra Health covers Curated provider network.
  • Prices and features above were last checked on 1 September 2026.

Where they differ

Only the attributes on which Annalise.ai and Lyra Health actually diverge.

Attributes where Annalise.ai and Lyra Health differ
AttributeAnnalise.aiLyra Health
PlatformsWeb, Cloud, On-premiseWeb, iOS, Android

Identical on both: starting price (On request), pricing model (quote), free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Annalise.ai

  • Annalise Enterprise CXR
  • Annalise Enterprise CTB
  • Triage and notification
  • Worklist reprioritisation
  • Localisation overlays
  • Confidence output
  • PACS-native deployment
  • On-premise or cloud inference

Only in Lyra Health

  • Curated provider network
  • Measurement based care
  • Self guided digital programmes
  • Coaching tier
  • Dependant and household coverage
  • Higher acuity pathways
  • Employer reporting
  • Global delivery

What people use each for

The jobs each tool is most often brought in to do.

Annalise.ai

  • An emergency department wanting pneumothorax and intracranial haemorrhage pushed to the front of the reading queue overnight when cover is thinnestnot Lyra Health
  • A teleradiology provider covering many small hospitals that needs consistent triage before a human readsnot Lyra Health
  • A screening programme in Europe where the broader CE marked decision support indication, rather than the narrow United States triage clearance, is what is being deployednot Lyra Health
  • A radiology department building an AI governance programme that wants one vendor covering both chest radiograph and head CT rather than contracting two separate algorithm suppliersnot Lyra Health

Lyra Health

  • An employer whose legacy employee assistance programme has utilisation in the low single digits and cannot demonstrate any clinical outcomenot Annalise.ai
  • A company with a distributed workforce needing therapist availability outside major metropolitan areas where the health plan network is thinnot Annalise.ai
  • An employer wanting behavioural health outcomes measured with validated instruments so the benefit can be evaluated rather than merely offerednot Annalise.ai
  • A multinational standardising mental health support across several countries under one contract and one reporting viewnot Annalise.ai

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Annalise.ai

  • The United States cleared indication covers roughly ten findings for triage and notification, far fewer than the model reports, so a buyer who evaluates the full multi-finding output and then contracts in the United States gets a much narrower cleared use.
  • Triage AI reprioritises a worklist but does not change clinical decisions on its own, so departments that do not redesign how urgent studies are picked up see no measurable improvement in time to treatment.
  • Published validation is largely reader study evidence on detection of individual findings; prospective evidence of shorter time to treatment in routine emergency care is thin.
  • The Annalise brand is being migrated under the Harrison.ai name for the critical care offering, which creates ambiguity in multi-year contracts about what product name is actually being supported.
  • A high finding count raises the alert burden, and departments report that low prevalence findings generate false positives that erode radiologist trust unless the alerting thresholds are tuned locally.

Lyra Health

  • Covered sessions per member per year are set in the employer contract and vary widely between clients, so employees at two companies both using Lyra can receive very different benefits and the number is never published.
  • When a member exhausts the employer funded session allowance, care transitions to the health plan network with its deductibles and copayments, or ends, and this handover is the most common source of employee dissatisfaction with the benefit.
  • The per employee per month fee is charged across the whole eligible population regardless of use, so an employer with low utilisation pays for the entire workforce to serve a small fraction of it.
  • Lyra costs materially more than a traditional employee assistance programme, and the business case depends on utilisation rising enough to justify the difference, which is not guaranteed by the contract.
  • International coverage is real but uneven, and a multinational will find provider depth and language availability in secondary markets well below what is available in the United States, which undermines the single global standard the contract implies.

Pricing, plan by plan

Annalise.ai

On request
  • Annalise Enterprise$undefined/year
    • Priced per study analysed or as an annual volume subscription
    • CXR and CTB licensed separately
    • Cleared finding set differs by market, which changes what you are buying

Lyra Health

On request
  • Lyra Health$undefined/year
    • Per employee per month fee across the eligible population, quoted not published
    • Covered sessions per member per year negotiated separately and varying widely by client
    • Dependant and household eligibility affects the rate

Which should you pick?

Choose Annalise.ai if

  • You need annalise enterprise cxr.
  • You work on Web, Cloud, On-premise.
  • You also want annalise enterprise ctb.
Annalise.ai review

Choose Lyra Health if

  • You need curated provider network.
  • You work on Web, iOS, Android.
  • You also want measurement based care.
Lyra Health review

Questions people ask

Is Annalise.ai or Lyra Health better?
Neither clearly leads. Annalise.ai starts at On request and Lyra Health at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Annalise.ai or Lyra Health?
Annalise.ai starts at On request and Lyra Health at On request.
Does Annalise.ai or Lyra Health run on more platforms?
Annalise.ai runs on Web, Cloud, On-premise. Lyra Health runs on Web, iOS, Android.
What is Annalise.ai best used for?
Annalise.ai is most often used for an emergency department wanting pneumothorax and intracranial haemorrhage pushed to the front of the reading queue overnight when cover is thinnest, a teleradiology provider covering many small hospitals that needs consistent triage before a human reads, a screening programme in europe where the broader ce marked decision support indication, rather than the narrow united states triage clearance, is what is being deployed, a radiology department building an ai governance programme that wants one vendor covering both chest radiograph and head ct rather than contracting two separate algorithm suppliers. Of those, an emergency department wanting pneumothorax and intracranial haemorrhage pushed to the front of the reading queue overnight when cover is thinnest and a teleradiology provider covering many small hospitals that needs consistent triage before a human reads are not what Lyra Health is typically brought in for.
What can Annalise.ai do that Lyra Health cannot?
Annalise.ai covers Annalise Enterprise CXR, Annalise Enterprise CTB, Triage and notification, Worklist reprioritisation. Lyra Health covers Curated provider network, Measurement based care, Self guided digital programmes, Coaching tier.

Answered from the vendors’ own pages

Annalise.ai: How many findings are FDA cleared?

Around ten across chest X-ray and head CT, for triage and notification only. The model reports far more findings than that; the rest are not cleared in the United States.

Lyra Health: How is Lyra priced?

Per employee per month across the eligible population, billed to the employer. The rate is quoted, never published, and depends on headcount, dependant eligibility and the contracted session allowance.

Annalise.ai: Is the European position different?

Yes. CE marking under the medical device regulation covers a broader decision support indication than the United States triage and notification clearances, so the same software is a different regulatory product depending on where you deploy it.

Lyra Health: How many therapy sessions do employees get?

It depends entirely on what the employer bought. Session allowances vary widely between clients, so ask your benefits team for the contracted number rather than assuming a standard.

Annalise.ai: Does it diagnose?

No. In the United States it is a triage and notification device: it flags studies for earlier review, and the radiologist makes the diagnosis.

Lyra Health: Who pays, the employer or the health plan?

The employer pays the per employee per month fee and funds the covered sessions. After the allowance is exhausted, cost typically shifts to the health plan and the member.

Annalise.ai: Is Annalise.ai becoming Harrison.ai?

The critical care offering is now marketed under the Harrison.ai name. Ask the vendor to name the contracted product explicitly before signing a multi-year deal.

Lyra Health: Is there a minimum headcount?

Lyra does not publish one, but it sells primarily to mid sized and large employers and the commercial model does not suit small companies.

Share

Related pages

More on Annalise.ai

More on Lyra Health

Keep looking

Other head to heads