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Healthcare · head to head

Annalise.ai vs Epic Systems

Annalise.ai logo

Annalise.ai

Healthcare

Multi-finding chest X-ray and head CT triage AI with FDA clearance on named findings, not on the whole model

From
On request
Rated
-
Epic Systems logo

Epic Systems

Healthcare

Leading electronic health records system for healthcare organizations

From
On request
Rated
-

The short version

  • Each has a real cost: Annalise.ai the United States cleared indication covers roughly ten findings for triage and notification, far fewer than the model reports, so a buyer who evaluates the full multi-finding output and then contracts in the United States gets a much narrower cleared use.; Epic Systems no free version or trial; enterprise pricing only with custom negotiation required
  • They diverge on capability: Annalise.ai covers Annalise Enterprise CXR, Epic Systems covers Electronic Health Records.
  • Prices and features above were last checked on 1 September 2026.

Where they differ

Only the attributes on which Annalise.ai and Epic Systems actually diverge.

Attributes where Annalise.ai and Epic Systems differ
AttributeAnnalise.aiEpic Systems
PlatformsWeb, Cloud, On-premiseWeb, Desktop, Mobile
FoundedUnknown1979

Identical on both: starting price (On request), pricing model (quote), free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Annalise.ai

  • Annalise Enterprise CXR
  • Annalise Enterprise CTB
  • Triage and notification
  • Worklist reprioritisation
  • Localisation overlays
  • Confidence output
  • PACS-native deployment
  • On-premise or cloud inference

Only in Epic Systems

  • Electronic Health Records
  • Revenue Cycle Management
  • Patient Portal
  • Clinical Decision Support
  • Population Health
  • Lab Systems
  • Imaging Systems
  • Pharmacy Systems

What people use each for

The jobs each tool is most often brought in to do.

Annalise.ai

  • An emergency department wanting pneumothorax and intracranial haemorrhage pushed to the front of the reading queue overnight when cover is thinnestnot Epic Systems
  • A teleradiology provider covering many small hospitals that needs consistent triage before a human readsnot Epic Systems
  • A screening programme in Europe where the broader CE marked decision support indication, rather than the narrow United States triage clearance, is what is being deployednot Epic Systems
  • A radiology department building an AI governance programme that wants one vendor covering both chest radiograph and head CT rather than contracting two separate algorithm suppliersnot Epic Systems

Epic Systems

  • Patient Carenot Annalise.ai
  • Medical Recordsnot Annalise.ai
  • Practice Managementnot Annalise.ai
  • Telehealthnot Annalise.ai

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Annalise.ai

  • The United States cleared indication covers roughly ten findings for triage and notification, far fewer than the model reports, so a buyer who evaluates the full multi-finding output and then contracts in the United States gets a much narrower cleared use.
  • Triage AI reprioritises a worklist but does not change clinical decisions on its own, so departments that do not redesign how urgent studies are picked up see no measurable improvement in time to treatment.
  • Published validation is largely reader study evidence on detection of individual findings; prospective evidence of shorter time to treatment in routine emergency care is thin.
  • The Annalise brand is being migrated under the Harrison.ai name for the critical care offering, which creates ambiguity in multi-year contracts about what product name is actually being supported.
  • A high finding count raises the alert burden, and departments report that low prevalence findings generate false positives that erode radiologist trust unless the alerting thresholds are tuned locally.

Epic Systems

  • No free version or trial; enterprise pricing only with custom negotiation required
  • Lengthy implementation timeline: 12-24 months for single hospitals, 3-5 years for multi-system rollouts
  • Customization and workflow adaptation requires extensive consulting services
  • Very high licensing costs ranging from 100,000 to 30 million USD depending on organization size

Pricing, plan by plan

Annalise.ai

On request
  • Annalise Enterprise$undefined/year
    • Priced per study analysed or as an annual volume subscription
    • CXR and CTB licensed separately
    • Cleared finding set differs by market, which changes what you are buying

Epic Systems

On request

No published plan breakdown. See the Epic Systems review.

Which should you pick?

Choose Annalise.ai if

  • You need annalise enterprise cxr.
  • You work on Web, Cloud, On-premise.
  • You also want annalise enterprise ctb.

Choose Epic Systems if

  • You need electronic health records.
  • You work on Web, Desktop, Mobile.
  • You also want revenue cycle management.

Questions people ask

Is Annalise.ai or Epic Systems better?
Neither clearly leads. Annalise.ai starts at On request and Epic Systems at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Annalise.ai or Epic Systems?
Annalise.ai starts at On request and Epic Systems at On request.
Does Annalise.ai or Epic Systems run on more platforms?
Annalise.ai runs on Web, Cloud, On-premise. Epic Systems runs on Web, Desktop, Mobile.
What is Annalise.ai best used for?
Annalise.ai is most often used for an emergency department wanting pneumothorax and intracranial haemorrhage pushed to the front of the reading queue overnight when cover is thinnest, a teleradiology provider covering many small hospitals that needs consistent triage before a human reads, a screening programme in europe where the broader ce marked decision support indication, rather than the narrow united states triage clearance, is what is being deployed, a radiology department building an ai governance programme that wants one vendor covering both chest radiograph and head ct rather than contracting two separate algorithm suppliers. Of those, an emergency department wanting pneumothorax and intracranial haemorrhage pushed to the front of the reading queue overnight when cover is thinnest and a teleradiology provider covering many small hospitals that needs consistent triage before a human reads are not what Epic Systems is typically brought in for.
What can Annalise.ai do that Epic Systems cannot?
Annalise.ai covers Annalise Enterprise CXR, Annalise Enterprise CTB, Triage and notification, Worklist reprioritisation. Epic Systems covers Electronic Health Records, Revenue Cycle Management, Patient Portal, Clinical Decision Support.

Answered from the vendors’ own pages

Annalise.ai: How many findings are FDA cleared?

Around ten across chest X-ray and head CT, for triage and notification only. The model reports far more findings than that; the rest are not cleared in the United States.

Epic Systems: What is Epic's market position?

Epic holds 36 percent of the U.S. EHR market and manages over 280 million patient records across 1,200+ healthcare organizations. Among hospitals with over 300 beds, Epic has 52 percent market share, and 71 percent market share in major academic medical centers as of 2026.

Source
Annalise.ai: Is the European position different?

Yes. CE marking under the medical device regulation covers a broader decision support indication than the United States triage and notification clearances, so the same software is a different regulatory product depending on where you deploy it.

Epic Systems: Is there a free trial or demo available?

Epic does not offer a free version or trial. The software is enterprise-only with custom pricing negotiated directly with organizations. Typical implementation timelines for single hospitals range from 12 to 24 months, and multi-hospital systems can take 3 to 5 years for phased rollouts.

Source
Annalise.ai: Does it diagnose?

No. In the United States it is a triage and notification device: it flags studies for earlier review, and the radiologist makes the diagnosis.

Epic Systems: How does Epic integrate with third-party systems?

Epic provides multiple integration pathways: FHIR R4 APIs, HL7 v2 messaging, CCDA document exchange, and proprietary APIs through Epic Showroom (formerly App Orchard). Over 1,000 certified apps are available in the marketplace, enabling real-time data synchronization and interoperability.

Source
Annalise.ai: Is Annalise.ai becoming Harrison.ai?

The critical care offering is now marketed under the Harrison.ai name. Ask the vendor to name the contracted product explicitly before signing a multi-year deal.

Epic Systems: What is included in Epic's unified platform?

Epic provides a truly unified system spanning inpatient, outpatient, emergency department, surgical, pharmacy, laboratory, radiology, billing, and population health on a single database. It includes appointment scheduling, medical billing, clinical decision support, patient portal (MyChart), telehealth capabilities, and analytics.

Source
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