Research · head to head
Obsidian vs Seven Bridges

Obsidian
Research
A powerful knowledge base on top of a local folder of plain text Markdown files
- From
- Free
- Rated
- -

Seven Bridges
Research
Cloud bioinformatics platform and trusted research environment, sold by Velsera
- From
- On request
- Rated
- -
The short version
- Only Obsidian has a free tier, so it costs nothing to try first.
- Each has a real cost: Obsidian sync is a paid add-on at $4 per month billed annually rather than part of the app; Seven Bridges the parent merged into Velsera in 2023 alongside Pierian and UgenTec, so the platform now competes for roadmap attention with clinical interpretation and diagnostics products inside a private equity owned group.
- They diverge on capability: Obsidian covers Bidirectional linking, Seven Bridges covers Trusted research environment.
- Prices and features above were last checked on 31 August 2026.
Where they differ
Only the attributes on which Obsidian and Seven Bridges actually diverge.
| Attribute | Obsidian | Seven Bridges |
|---|---|---|
| Starting price | Free | On request |
| Pricing model | Unknown | quote |
| Free tier | Yes | No |
| Platforms | Web, Windows, macOS, Linux, iOS, Android | Web, API, Cloud |
| Founded | 2020 | Unknown |
Identical on both: user rating (Not yet rated), category (Research).
What each one covers
Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.
Only in Obsidian
- Bidirectional linking
- Graph view visualization
- Markdown support
- Local file storage
- Plugin ecosystem
- Custom CSS themes
- Templates
- Search and tags
Only in Seven Bridges
- Trusted research environment
- Cloud-agnostic
- CWL pipelines
- Compliance certifications
- Cost prediction
- Public data commons
- Collaboration
- Tool library
What people use each for
The jobs each tool is most often brought in to do.
Obsidian
- Local-first markdown note taking with no account requirednot Seven Bridges
- Linking notes into a personal knowledge graphnot Seven Bridges
- Syncing a vault across devices with end-to-end encryption on the paid add-onnot Seven Bridges
- Publishing a public site from a vaultnot Seven Bridges
- Extending the editor with community pluginsnot Seven Bridges
Seven Bridges
- A cancer genomics group analysing controlled-access dbGaP data that cannot be moved to local infrastructurenot Obsidian
- A federal or federally funded programme that needs FedRAMP Moderate authorisation for its analysis environmentnot Obsidian
- A multi-institution consortium sharing pipelines and results under defined access controls rather than by emailing filesnot Obsidian
- A diagnostics developer building reproducible CWL pipelines that must stand up to later regulatory reviewnot Obsidian
Where each one falls short
Documented limitations, not opinions. Every one is a constraint you would hit in normal use.
Obsidian
- Sync is a paid add-on at $4 per month billed annually rather than part of the app
- Publishing to the web is a further $8 per month per site
- Commercial use asks for a $50 per user per year licence, though the vendor states it is not required
- Collaboration is limited compared with a hosted notes tool, since the vault is local files first
Seven Bridges
- The parent merged into Velsera in 2023 alongside Pierian and UgenTec, so the platform now competes for roadmap attention with clinical interpretation and diagnostics products inside a private equity owned group.
- Pricing is not published and splits into a platform subscription plus consumption-based cloud compute, so a heavy analysis quarter produces a bill that headcount-based budgeting does not anticipate.
- The analysis capability itself has credible open source equivalents in Nextflow and Cromwell on raw cloud, so you are principally paying for compliance and governance rather than for the science.
- Pipelines are built around Common Workflow Language, which is a real learning curve and a portability commitment for teams whose existing work is in other workflow languages.
- Cloud storage of large genomic datasets accrues continuously whether or not you are analysing, and egress charges apply when moving results out, both of which are outside the subscription line.
Pricing, plan by plan
Obsidian
Free- Obsidian Sync$4/month
- Sync notes across devices
- Obsidian Publish$8/month
- Turn notes into a website
Seven Bridges
On request- Seven Bridges Platform$undefined/year
- Platform subscription quoted through Velsera sales
- Cloud compute and storage charged on consumption on top of the subscription
- Cost predictor tools provided to estimate analysis spend in advance
Which should you pick?
Choose Obsidian if
- You need bidirectional linking.
- You want to start without paying.
- You work on Web, Windows, macOS, Linux, iOS, Android.
- You also want graph view visualization.
Choose Seven Bridges if
- You need trusted research environment.
- You work on Web, API, Cloud.
- You also want cloud-agnostic.
Questions people ask
- Is Obsidian or Seven Bridges better?
- Neither clearly leads. Obsidian starts at Free and Seven Bridges at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
- Which is cheaper, Obsidian or Seven Bridges?
- Obsidian has a free tier; the other does not. Paid plans start at Free for Obsidian and On request for Seven Bridges.
- Does Obsidian or Seven Bridges run on more platforms?
- Obsidian runs on Web, Windows, macOS, Linux, iOS, Android. Seven Bridges runs on Web, API, Cloud.
- Can I use Obsidian for free?
- Yes. Obsidian has a free tier, so you can try it without paying. Seven Bridges starts at On request.
- What is Obsidian best used for?
- Obsidian is most often used for local-first markdown note taking with no account required, linking notes into a personal knowledge graph, syncing a vault across devices with end-to-end encryption on the paid add-on, publishing a public site from a vault. Of those, local-first markdown note taking with no account required and linking notes into a personal knowledge graph are not what Seven Bridges is typically brought in for.
- What can Obsidian do that Seven Bridges cannot?
- Obsidian covers Bidirectional linking, Graph view visualization, Markdown support, Local file storage. Seven Bridges covers Trusted research environment, Cloud-agnostic, CWL pipelines, Compliance certifications.
Answered from the vendors’ own pages
Obsidian: Is Obsidian free?
Yes. The core Obsidian application is 100% free for personal and commercial use with no limitations. You can use unlimited vaults and every core feature without payment.
SourceSeven Bridges: Is Seven Bridges still sold?
Yes. It is sold by Velsera, formed in 2023 when Summa Equity merged Seven Bridges with Pierian and UgenTec. The Seven Bridges name was retained for the platform.
Obsidian: What file format does Obsidian use?
Obsidian stores every note as a plain Markdown file. Because it uses standard Markdown instead of a proprietary format, your notes remain portable and can be edited with many other Markdown editors.
SourceSeven Bridges: What compliance does it hold?
FedRAMP Moderate, SOC 2, HIPAA, GDPR, dbGaP and ISO 27001, 27017, 27018 and 27701, which is the usual reason institutions choose it over building on raw cloud.
Obsidian: Can I collaborate with others in Obsidian?
The core application does not include built-in team collaboration features. However, Obsidian offers optional add-ons and can be used with version control systems or cloud storage for collaboration.
SourceSeven Bridges: How is it priced?
Not published. Expect a platform subscription plus consumption charges for cloud compute and storage.
Seven Bridges: Do I have to use a specific cloud?
No. The platform is cloud-agnostic and designed to bring analysis to where the data already resides.
Related pages
More on Seven Bridges
Other head to heads
- Obsidian vs Roam Research
- Obsidian vs Elicit
- Obsidian vs Mendeley
- Obsidian vs NVivo
- Obsidian vs Paperpile
- Obsidian vs Zotero
- Obsidian vs Wolfram Mathematica
- Obsidian vs SurveyMonkey
- Obsidian vs Aurelius
- Obsidian vs Benchling
- Obsidian vs LabVantage
- Obsidian vs Sapio Sciences
- Obsidian vs Castor EDC
- Obsidian vs Chemaxon
- Obsidian vs Condens
- Obsidian vs DNAnexus
- Obsidian vs Dotmatics
- Obsidian vs Terra
- Obsidian vs Form Bio
- Obsidian vs Labguru
- Obsidian vs Genedata
- Obsidian vs Greenphire
- Obsidian vs Medidata Rave
- Obsidian vs OpenEye, Cadence Molecular Sciences
- Obsidian vs Attest
- Obsidian vs Schrodinger
- Obsidian vs Scispot
- Obsidian vs Suzy
- Obsidian vs TetraScience
- Obsidian vs Thermo SampleManager LIMS
- Seven Bridges vs Roam Research
- Seven Bridges vs Elicit
- Seven Bridges vs Mendeley
- Seven Bridges vs NVivo
- Seven Bridges vs Paperpile
- Seven Bridges vs Zotero
- Seven Bridges vs Wolfram Mathematica
- Seven Bridges vs SurveyMonkey
- Seven Bridges vs Aurelius
- Seven Bridges vs Benchling
- Seven Bridges vs LabVantage
- Seven Bridges vs Sapio Sciences
- Seven Bridges vs Castor EDC
- Seven Bridges vs Chemaxon
- Seven Bridges vs Condens
- Seven Bridges vs DNAnexus
- Seven Bridges vs Dotmatics
- Seven Bridges vs Terra
- Seven Bridges vs Form Bio
- Seven Bridges vs Labguru
- Seven Bridges vs Genedata
- Seven Bridges vs Greenphire
- Seven Bridges vs Medidata Rave
- Seven Bridges vs OpenEye, Cadence Molecular Sciences
- Seven Bridges vs Attest
- Seven Bridges vs Schrodinger
- Seven Bridges vs Scispot
- Seven Bridges vs Suzy
- Seven Bridges vs TetraScience
- Seven Bridges vs Thermo SampleManager LIMS
