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Healthcare · head to head

eClinicalWorks Prime vs UpToDate

eClinicalWorks Prime logo

eClinicalWorks Prime

Healthcare

AI-powered cloud EHR for modern healthcare practices

From
$180/month
Rated
-
Full reviewWebsite
UpToDate logo

UpToDate

Healthcare

Evidence-based clinical decision support for healthcare providers

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: eClinicalWorks Prime eHR Only is $449/month per provider and EHR with Practice Management is $599/month per provider, priced per provider rather than a flat practice fee; UpToDate upToDate does not publish subscription prices; the vendor (Wolters Kluwer) sorts buyers into separate individual, clinic-wide, and institutional subscription tracks and requires contacting the organization through its subscription-payment-options page rather than showing a rate for any of them.
  • They diverge on capability: eClinicalWorks Prime covers Electronic Health Records, UpToDate covers Clinical Evidence.
  • Prices and features above were last checked on 30 August 2026.

Where they differ

Only the attributes on which eClinicalWorks Prime and UpToDate actually diverge.

Attributes where eClinicalWorks Prime and UpToDate differ
AttributeeClinicalWorks PrimeUpToDate
Starting price$180/monthOn request
PlatformsWeb, Mobile, ApiWeb, Mobile
Founded19991992

Identical on both: pricing model (subscription), free tier (No), user rating (Not yet rated), category (Healthcare).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in eClinicalWorks Prime

  • Electronic Health Records
  • AI-Assisted Documentation
  • Practice Management
  • Revenue Cycle
  • Patient Portal
  • Voice Recognition
  • Telehealth
  • HL7

Only in UpToDate

  • Clinical Evidence
  • Drug Information
  • Calculators
  • Medical Images
  • Videos
  • CME Credits
  • EHR Systems
  • Mobile

Both cover

  • HIPAA
  • Cloud deployment
  • Web support
  • Mobile support

What people use each for

The jobs each tool is most often brought in to do.

eClinicalWorks Prime

  • Small to mid-size practices (1-9 providers) wanting per-provider EHR pricing with included trainingnot UpToDate

UpToDate

  • Patient Carenot eClinicalWorks Prime
  • Medical Recordsnot eClinicalWorks Prime
  • Practice Managementnot eClinicalWorks Prime
  • Telehealthnot eClinicalWorks Prime

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

eClinicalWorks Prime

  • EHR Only is $449/month per provider and EHR with Practice Management is $599/month per provider, priced per provider rather than a flat practice fee
  • The RCM as a Service option charges 2.9% of practice collections rather than a fixed fee
  • Practices with more than 9 providers are charged additional implementation fees beyond the included training

UpToDate

  • UpToDate does not publish subscription prices; the vendor (Wolters Kluwer) sorts buyers into separate individual, clinic-wide, and institutional subscription tracks and requires contacting the organization through its subscription-payment-options page rather than showing a rate for any of them.

Pricing, plan by plan

eClinicalWorks Prime

$180/month

No published plan breakdown. See the eClinicalWorks Prime review.

UpToDate

On request

No published plan breakdown. See the UpToDate review.

Which should you pick?

Choose eClinicalWorks Prime if

  • You need electronic health records.
  • You work on Web, Mobile, Api.
  • You also want ai-assisted documentation.
eClinicalWorks Prime review

Choose UpToDate if

  • You need clinical evidence.
  • You work on Web, Mobile.
  • You also want drug information.
UpToDate review

Questions people ask

Is eClinicalWorks Prime or UpToDate better?
Neither clearly leads. eClinicalWorks Prime starts at $180/month and UpToDate at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, eClinicalWorks Prime or UpToDate?
eClinicalWorks Prime starts at $180/month and UpToDate at On request.
Does eClinicalWorks Prime or UpToDate run on more platforms?
eClinicalWorks Prime runs on Web, Mobile, Api. UpToDate runs on Web, Mobile.
What is eClinicalWorks Prime best used for?
eClinicalWorks Prime is most often used for small to mid-size practices (1-9 providers) wanting per-provider ehr pricing with included training. Of those, small to mid-size practices (1-9 providers) wanting per-provider ehr pricing with included training is not what UpToDate is typically brought in for.
What can eClinicalWorks Prime do that UpToDate cannot?
eClinicalWorks Prime covers Electronic Health Records, AI-Assisted Documentation, Practice Management, Revenue Cycle. UpToDate covers Clinical Evidence, Drug Information, Calculators, Medical Images. Both handle HIPAA, Cloud deployment, Web support, Mobile support.

Answered from the vendors’ own pages

eClinicalWorks Prime: How much does eClinicalWorks Prime cost?

eClinicalWorks does not publish pricing for its Prime RCM (Revenue Cycle Management) service. The vendor positions it as 'Better RCM service at a lower price than your current provider' but requires interested organizations to schedule a demo or contact sales at 508-836-2700 for custom pricing based on organizational size and specific requirements.

Source
eClinicalWorks Prime: How can you get eClinicalWorks Prime pricing?

Contact eClinicalWorks directly at 508-836-2700 to speak with their sales team or schedule a demo to discuss pricing tailored to your organization.

Source
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