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Cybersecurity · head to head

Microsoft Defender vs Qualys VMDR

Microsoft Defender logo

Microsoft Defender

Cybersecurity

Always-on protection for you and your family's data and devices

From
$12/month
Rated
-
Full reviewWebsite
Qualys VMDR logo

Qualys VMDR

Cybersecurity

Cloud-delivered vulnerability management licensed per asset, using scanner appliances and a lightweight agent.

From
$3/month
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: Microsoft Defender defender Suite requires existing Microsoft 365 E3 or equivalent base licensing; Qualys VMDR licensing is per asset and each capability is its own subscription, so patch management, endpoint detection, web application scanning, container security and policy compliance are separate line items, and the platform demonstrated in a proof of concept is rarely the platform in the quote.
  • Prices and features above were last checked on 30 August 2026.

Where they differ

Only the attributes on which Microsoft Defender and Qualys VMDR actually diverge.

Attributes where Microsoft Defender and Qualys VMDR differ
AttributeMicrosoft DefenderQualys VMDR
Starting price$12/month$3/month
PlatformsWebWeb, Cloud, Api
FoundedUnknown1999

Identical on both: pricing model (subscription), free tier (No), user rating (Not yet rated), category (Cybersecurity).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in Microsoft Defender

Nothing recorded that Qualys VMDR does not also cover.

Only in Qualys VMDR

  • Cloud Agent
  • Scanner appliances
  • Authenticated scanning
  • TruRisk scoring
  • Asset inventory
  • Patch Management
  • Cloud connectors
  • Container sensor

What people use each for

The jobs each tool is most often brought in to do.

Microsoft Defender

  • Endpoint security and threat protectionnot Qualys VMDR
  • Identity and access securitynot Qualys VMDR
  • Email threat protectionnot Qualys VMDR
  • SaaS application security monitoringnot Qualys VMDR

Qualys VMDR

  • A hybrid workforce where scheduled network scans miss most laptops and continuous agent-based assessment is the only way to get real coveragenot Microsoft Defender
  • PCI DSS external scanning where an approved scanning vendor report is a contractual requirementnot Microsoft Defender
  • An estate spanning datacentre, multiple public clouds and endpoints that needs one vulnerability view rather than three toolsnot Microsoft Defender
  • Organisations replacing a manual patch-verification process with agent-reported evidence that a fix actually landednot Microsoft Defender

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

Microsoft Defender

  • Defender Suite requires existing Microsoft 365 E3 or equivalent base licensing
  • Some Defender products use pay-as-you-go pricing with variable costs
  • Prices vary based on Microsoft agreements, requiring sales contact for custom quotes

Qualys VMDR

  • Licensing is per asset and each capability is its own subscription, so patch management, endpoint detection, web application scanning, container security and policy compliance are separate line items, and the platform demonstrated in a proof of concept is rarely the platform in the quote.
  • Ephemeral cloud instances consume asset entitlement until they age out of inventory, so an autoscaling group that creates and destroys hosts hourly can burn licence capacity on machines that existed for minutes, and controlling that means tuning purge policies rather than tuning the cloud.
  • Authenticated scanning produces materially better results than unauthenticated, but it requires storing and rotating privileged credentials for every target platform, which is a security project in its own right, and teams that skip it receive reports full of unconfirmed potential findings that nobody trusts.
  • The console is a set of modules with separate interfaces, search syntaxes and report engines, so an analyst moving between vulnerability management, policy compliance and web application scanning learns each one, and cross-module reporting usually ends in a spreadsheet or a script against the API.
  • The tool surfaces findings far faster than any organisation can remediate them, and it does not solve the ownership problem: without an agreed prioritisation policy and a named owner in IT operations, a first scan producing tens of thousands of findings becomes a dashboard that everyone learns to ignore.

Pricing, plan by plan

Microsoft Defender

$12/month
  • Microsoft Defender Suite$12/month
    • Endpoint protection
    • Identity threat detection
    • Email security
  • Microsoft 365 E5 with Defender$60/month
    • Includes Defender Suite
    • Microsoft Teams included
    • Comprehensive security and compliance
  • Microsoft Defender Vulnerability Management Add-on$2/month
    • Vulnerability scanning and management
    • One-month free trial available
    • Annual commitment required

Qualys VMDR

$3/month
  • VMDR$3/month
    • Per asset
    • Vulnerability scanning
    • Detection
  • VMDR+$5/month
    • All VMDR features
    • Advanced analytics
    • Cloud integration
  • VMDR Complete$7/month
    • All VMDR+ features
    • Threat intel
    • Response automation

Which should you pick?

Choose Microsoft Defender if

Nothing in the data separates Microsoft Defender from Qualys VMDR on the points above - pick on price and on how each one feels to use.

Microsoft Defender review

Choose Qualys VMDR if

  • You need cloud agent.
  • You work on Web, Cloud, Api.
  • You also want scanner appliances.
Qualys VMDR review

Questions people ask

Is Microsoft Defender or Qualys VMDR better?
Neither clearly leads. Microsoft Defender starts at $12/month and Qualys VMDR at $3/month, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, Microsoft Defender or Qualys VMDR?
Microsoft Defender starts at $12/month and Qualys VMDR at $3/month.
Does Microsoft Defender or Qualys VMDR run on more platforms?
Microsoft Defender runs on Web. Qualys VMDR runs on Web, Cloud, Api.
What is Microsoft Defender best used for?
Microsoft Defender is most often used for endpoint security and threat protection, identity and access security, email threat protection, saas application security monitoring. Of those, endpoint security and threat protection and identity and access security are not what Qualys VMDR is typically brought in for.
What can Microsoft Defender do that Qualys VMDR cannot?
Qualys VMDR covers Cloud Agent, Scanner appliances, Authenticated scanning, TruRisk scoring.

Answered from the vendors’ own pages

Microsoft Defender: How much does Microsoft Defender Suite cost?

Microsoft Defender Suite costs $12/user/month (paid yearly), but requires existing Microsoft 365 E3 or equivalent base licensing. It includes endpoint protection, identity threat detection, email security, and SaaS application monitoring.

Source
Qualys VMDR: Agent or scanner: which do I need?

Usually both. The agent covers endpoints and servers you control and gives continuous data; scanners cover devices you cannot install an agent on, such as network gear, printers and appliances, and provide the external perimeter view.

Microsoft Defender: What add-ons are available for Microsoft Defender?

Microsoft Defender Vulnerability Management Add-on costs $2/user/month with annual commitment and includes a one-month free trial. Additional pay-as-you-go products include External Attack Surface Management, Cloud Security Posture Management, and Sentinel.

Source
Qualys VMDR: Does it patch as well as detect?

Yes, through the Patch Management module, which is a separate subscription using the same agent. Core VMDR detects and prioritises but does not deploy fixes.

Microsoft Defender: Is Defender included in Microsoft 365 E5?

Yes, Microsoft Defender Suite is included in Microsoft 365 E5 at $60/user/month (paid yearly with Teams). Prices may vary based on Microsoft agreements, requiring contact with Sales for customized quotes.

Source
Qualys VMDR: How are assets counted for licensing?

By the number of assets in inventory, which includes cloud instances and containers depending on the modules in use. Short-lived cloud assets count until they are purged, so purge settings directly affect what you consume.

Qualys VMDR: Can I keep the data in a specific region?

Yes. Qualys operates several regional platform instances and you choose which one your subscription lives on. Moving between them later is not trivial, so decide before onboarding.

Qualys VMDR: Does it scan web applications?

Web Application Scanning is a separate module licensed per application, not part of core VMDR, and it is a dynamic scanner with the usual limits around authenticated flows in single-page applications.

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