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AI · head to head

CoreWeave vs DNAnexus

CoreWeave logo

CoreWeave

AI

Specialized cloud for GPU compute

From
$0.35/per-hour
Rated
-
Full reviewWebsite
DNAnexus logo

DNAnexus

Research

Regulated cloud platform for genomic and multiomic data, with GxP and FedRAMP coverage

From
On request
Rated
-
Full reviewWebsite

The short version

  • Each has a real cost: CoreWeave gPU nodes are sold as full 8 GPU instances rather than single cards, so the entry cost for an H100 node is $49.24 an hour on demand; DNAnexus no pricing is published, so an organisation cannot compare the total cost against running the same pipelines on its own cloud account until it is deep in a sales process.
  • They diverge on capability: CoreWeave covers NVIDIA H100/A100, DNAnexus covers Governed data storage.
  • Prices and features above were last checked on 31 August 2026.

Where they differ

Only the attributes on which CoreWeave and DNAnexus actually diverge.

Attributes where CoreWeave and DNAnexus differ
AttributeCoreWeaveDNAnexus
Starting price$0.35/per-hourOn request
Pricing modelusage-basedquote
PlatformsCloudWeb, Linux
CategoryAIResearch
Founded2017Unknown

Identical on both: free tier (No), user rating (Not yet rated).

What each one covers

Drawn from each product's published feature list. An absence here means we hold no record of it - not that the product lacks it.

Only in CoreWeave

  • NVIDIA H100/A100
  • Kubernetes native
  • High bandwidth
  • Object storage
  • Kubernetes
  • Terraform
  • Cloud APIs
  • Cloud support

Only in DNAnexus

  • Governed data storage
  • Workflow execution
  • App building
  • Controlled collaboration
  • Compliance posture
  • Cohort browsing

What people use each for

The jobs each tool is most often brought in to do.

CoreWeave

  • Renting GPU compute for model training and inferencenot DNAnexus
  • Running large scale AI workloads without buying hardwarenot DNAnexus

DNAnexus

  • A clinical diagnostics laboratory that needs a CLIA and CAP aligned environment for production sequencing pipelines without building the compliance evidence itselfnot CoreWeave
  • A pharma sponsor analysing genomic endpoints in a registrational programme where 21 CFR Part 11 records are requirednot CoreWeave
  • A biobank or consortium giving hundreds of external researchers governed access to a dataset too large to distributenot CoreWeave
  • A diagnostics vendor packaging its pipeline as a versioned app so partner laboratories can run it without receiving the source codenot CoreWeave

Where each one falls short

Documented limitations, not opinions. Every one is a constraint you would hit in normal use.

CoreWeave

  • GPU nodes are sold as full 8 GPU instances rather than single cards, so the entry cost for an H100 node is $49.24 an hour on demand
  • Spot pricing is roughly 40% of on demand, at $19.71 an hour for the same H100 node, so predictable capacity carries a large premium
  • The newest hardware carries no published price and requires contacting sales
  • Discounts of up to 60% require committed usage agreements negotiated with sales
  • Only the GH200 is offered as a single GPU instance

DNAnexus

  • No pricing is published, so an organisation cannot compare the total cost against running the same pipelines on its own cloud account until it is deep in a sales process.
  • Compute and storage are billed through the platform rather than at underlying cloud list price, so the compliance envelope carries a persistent margin on every terabyte and core hour, which grows with the science rather than staying fixed.
  • Data egress at genomic scale is slow and chargeable, so leaving the platform later is a real project rather than a contract decision, and that gravity weakens negotiating position at renewal.
  • The regulated and validated configurations sit in a higher commercial tier than the research configuration, so an organisation that starts in research mode and later needs GxP faces a repricing rather than a setting change.
  • Bioinformaticians used to running Nextflow on their own infrastructure find the platform abstractions constraining, and porting an existing pipeline into the app model is engineering work that does not carry over to any other platform.

Pricing, plan by plan

CoreWeave

$0.35/per-hour
  • Standard$0.35/per-hour
    • Various GPU types
    • Kubernetes
  • EnterpriseFree
    • Dedicated clusters
    • Custom solutions

DNAnexus

On request
  • DNAnexus Platform$undefined/year
    • Quoted per organisation through a sales process
    • Storage and compute billed through the platform rather than at cloud list price
    • Regulated and validated configurations are a separate commercial tier

Which should you pick?

Choose CoreWeave if

  • You need nvidia h100/a100.
  • You work on Cloud.
  • You also want kubernetes native.
CoreWeave review

Choose DNAnexus if

  • You need governed data storage.
  • You work on Web, Linux.
  • You also want workflow execution.
DNAnexus review

Questions people ask

Is CoreWeave or DNAnexus better?
Neither clearly leads. CoreWeave starts at $0.35/per-hour and DNAnexus at On request, and user ratings are close enough to be indistinguishable. Choose on capability and platform support.
Which is cheaper, CoreWeave or DNAnexus?
CoreWeave starts at $0.35/per-hour and DNAnexus at On request.
Does CoreWeave or DNAnexus run on more platforms?
CoreWeave runs on Cloud. DNAnexus runs on Web, Linux.
What is CoreWeave best used for?
CoreWeave is most often used for renting gpu compute for model training and inference, running large scale ai workloads without buying hardware. Of those, renting gpu compute for model training and inference and running large scale ai workloads without buying hardware are not what DNAnexus is typically brought in for.
What can CoreWeave do that DNAnexus cannot?
CoreWeave covers NVIDIA H100/A100, Kubernetes native, High bandwidth, Object storage. DNAnexus covers Governed data storage, Workflow execution, App building, Controlled collaboration.

Answered from the vendors’ own pages

CoreWeave: How much does CoreWeave cost?

CoreWeave does not publish pricing on its website. The company uses a quote-based pricing model and directs customers to contact their sales team directly to discuss pricing options and customized solutions.

Source
DNAnexus: Why pay for DNAnexus instead of raw AWS?

For the compliance evidence. GxP, FedRAMP, CLIA, CAP and Part 11 coverage removes a validation programme most organisations would otherwise have to build and maintain themselves.

CoreWeave: How can I get a quote from CoreWeave?

To obtain CoreWeave pricing, you must contact their sales team directly through the Contact Us option on their website. They will provide a customized quote based on your specific compute and infrastructure requirements.

Source
DNAnexus: Is validated use included?

No. Regulated and validated configurations sit in a separate commercial tier from ordinary research use.

DNAnexus: Can I get my data out?

Yes, but egress at genomic scale is chargeable and slow, so plan exit costs at the point of signing.

DNAnexus: Does it host UK Biobank?

Yes, DNAnexus hosts the UK Biobank research analysis platform, which has its own access approval and cost terms.

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